276 



INTRACELLULAR LUMINESCENCE 



12 3 4 5 6 7 



Minutes 



Fig. 7. The influence of hydrostatic pressure on the relati\e rate of destruction of 

 the luminescent system of P. plwsplioreum suspended in phospliate-buffered 

 sodium chloride of neutral pH at 34° C. ( From Johnson, Eyring, and Polis- 

 sar, 1954, courtesy of John Wiley & Sons; data of Johnson et al., 1945.) 



of the reversible thermal denaturation of an essential enzyme. In 

 effect, the drug combines with the reversibly denatured form, and 

 the amount of denatured enzyme then becomes significant at a lower 



