22 



The Chemistry of the Injured Cell 



severe fatty change after forty-eight hours. Liver fat may then be 

 high as 15 per cent (controls 6.11 ± 0.94 per cent) , and is mainly 

 neutral fat esters, with no increase in total cholesterol and phospho- 

 lipid (Snyder et al., 1959) . 



Some useful information about the human fatty liver is summar- 

 ised in the following table condensed from Ralli et al, (1941) . 



Mean Values of Lipids in Normal, Fatty (alcoholic) and 

 Cirrhotic Livers (wet weights) 



Normal 

 (25 cases) 



Alcoholics 

 with fatty 

 livers 



(25 cases) 



Cirrhosis 

 of liver 



(5 cases) 



4.98 



12.20 



3.50 



11.80 



283 



324 



2.08 



1.72 



2.26 



11.4 



4.94 



3.95 



283 



1.51 



3.7 



The range of total lipids in these 25 normal livers was 2.42-8.41 g. per 100 g. wet 

 tissue. In the 25 alcoholic cases, 13 had lipid values over 9 g. per 100 g. 



The next table gives more information expressed rather differ- 

 ently. It includes some of the figures of Ralli et al. re-calculated so as 

 to be comparable with the data of Man et al. 



Range of Lipids in Normal and Diseased Livers, the Latter 

 Mostly Affected by Fatty Change (Man et al) 



