54 



The Chemistry of the Injured Cell 



Oxaloacetate- 

 3ATP 



0*- 



-2H 



IDPN) 



Ma 



H 2 0- 



8 



ate 



Fumarate 



A 



2ATP 



0<- 



-2H 



Succinates- 



1ATP 



Pyruvate 



Acety 



-2H 



IDPN) 

 3ATP > 



->0 



-co 2 



CoA 



k. 



Succinyl 

 CoA 



«T 



3ATP I 

 -C0 2 -2H 

 S IDPN) 



I 







-^Citrate 



Cisaconitate 

 3 



Isocitrate 

 4 



•H,0 



H,0 



-2H 



(TPN) 

 3ATP^ 



-C0 2 ' 

 •ex. ketoglutarate 



Fig. 6. The Tricarboxylic Acid (TCA, Krebs) Cycle. 



1. Pyruvic oxidase. 



2. Condensing enzyme. 



3. Aconitase. 



4. Isocitric dehydrogenase. 



5. a ketoglutaric oxidase. 



6. Succinic dehydrogenase. 



7. Fumarase. 



8. Malic dehydrogenase. 



->0 



