Fats 27 



tion to this galactocerebroside, there is in Gaucher's disease storage 

 of an abnormal gluco-cerebroside not found elsewhere. The nature 

 of the disorder of cerebroside metabolism in Gaucher's disease is 

 unknown. However, lignoceryl sphingosine normally combines 

 with choline to form the important substance sphingomyelin. It 

 has been suggested that if this reaction were defective due to a 

 genetic fault there would be an excess of lignoceryl sphingosine 

 free to combine with galactose and glucose to form galacto- and 

 gluco-cerebroside in abnormal quantities. 



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