144 



Index 



Chlorpromazine, anti-metabolic action. 



78 

 Choline as lipotropic agent, 19, 20 



phosphorylation, 24 

 Clostridium welchii toxins, anti-metabo- 

 lic action, 79 

 Cloudy swelling, 5, 41 

 Collagen formation, 125 

 Copper deficiency and demyelination, 



104, 105 



effects, 60 

 Corticotropin, effect on glycogen stores, 



31 

 Cortisone, effect on glycogen stores, 32 

 Cretinism, goitrous, 65 

 Cyanide, mode of action, 57 

 Cyanocobalamin, effects of deficiency, 64 

 Cystine deficiency and liver necrosis, 83 



lipotropic action, 19 

 Cytidine-diphospho-choline, 24 

 Cytochrome c, cardiac, 89 



oxidase, 72 

 cardiac, 89 



effects of deficiency, 60 

 Cytoplasm, vacuolation, 5, 97 



D 



Deficiency states and respiratory enzy- 

 mes, 59 



Demyelination, 101-106 



Deoxyadenosine 5'phosphate, 37 



Deoxyadenylate, 37 



Deoxycytidinate, 37 



Deoxyguanylate, 37 



Deoxyribonucleic acid, 36, 38 

 control of protein synthesis, 40 

 decrease in autolysis, 98 

 effect of carbon tetrachloride on, 44 

 in thyroid crisis, 43 



d-2-Deoxyribose, 36 



Desoxyribonuclease release in autolysis, 

 98 



Dextrin phosphorylase limit, 31 



DFP, toxic effects, 63 



Diabetes mellitus, 62 



Dimercaprol, protective action against 

 triethyl tin compounds, 79 



Dimethylnitrosamine, anti-metabolic ac- 

 tion, 77 



2:4-Dinitrophenol 



effect on glycogen storage, 34 



mode of action as respiratory poison, 



57 

 Diphtheria toxin, anti-metabolic action, 



79 



Electrolyte metabolism of cells, 5-17 

 uptake of injured cells, 7 



Electron transport, 50 



Endotoxins, bacterial, 126, 129, 136, 137 



Enzymes, 49-68 



deficiencies, genetically determined, 64 

 loss in cellular autolysis, 98 

 non-respiratory, effects of injury, 60 

 proteolytic, in shock, 138 

 respiratory, effects of injury, 53 



Erythrocytes, abnormalities, 64 



Factor 3 and dietary necrosis, 84 



Fat content of cells, physiological influ- 

 ences, 20 



Fats, 18-27 



types accumulated in damaged cells, 

 21 



Fatty acids, oxidation, 26 

 change, 18-26 



significance, 24 

 degeneration, 18, 19 



Favism, 65 



Ferritin in shock, 136 



Fever in inflammation, 126 



Fluoroacetate, mode of action as respira- 

 tory poison, 58 



Folic acid, effects of deficiency, 64 



G 



Calactosaemia, 66 



Gaucher s disease, 26 



Globulins, plasma, abnormal, 46 



Gluconeogenesis, 31, 32, 34 



Glucose 



breakdown, 50 

 conversion to glycogen, 29 



Glucose-6-phosphate-dehydrogenase, con- 

 genital absence, 65 



^-Glucuronidase release in autolysis, 98 



