146 



Index 



fat content, 21 

 fatty, lipid values, 22, 23 

 hypertrophy, compensatory, 42 

 injury, electrolytic changes, 13 

 necrosis, dietary, 83-87 

 chemistry of liver cells, 85 

 structural changes, 84 

 Lupus erythematosis, 46 

 Lysosomes, changes in autolysis, 98 



M 



Macroglobulinaemia, 42, 46 



Malnutrition, effect on protein and de- 

 oxyribonucleic acid, 43 



L-Meromyosin, 90 



Metabolism, aerobic, 72 



Methaemoglobinaemia, congenital, 64 



Methionine, lipotropic action, 19 



Microsomes as sites of protein synthesis, 

 39 



Mipafox, toxic effects, 63 



Mitochondria as sites of protein synthe- 

 sis, 39 



effects of injury, 55 

 glycolytic activity, 71 

 swollen, 5, 7 



Monoamine oxidase inhibitors, 116, 117 



Myelin sheath, structure, 101 



Myelination, 101 

 chemistry, 102 



Myelomatosis, 46 



Myocardial cell 



damage due to anoxia, 88-96 



response to anoxia and haemorrhagic 



shock, 93 

 response to ischaemia, 92 



Myokinase, 90 



Myosin, 90 



N 

 Nerve fibres, demyelination, 101-106 

 Neutropenia, 130 



Nicotinic acid, effects of deficiency, 59 

 Nitrogen 



excretion in shock, 133 



mustard, mode of action as respiratory 

 poison, 58 

 Noradrenaline release in shock, 135 



Nucleic acids, 36 



Nucleoproteins of normal cell, 36, 38 



o 



Oestrogens, effect on uterine gland cells, 

 43 



Pain in inflammation, 125 

 Pantothene, effects of deficiency, 60 

 Parathion, toxic effects, 63 

 Peptides, role in inflammation, 112 

 Phenergan, protective action against 



carbon tetrachloride, 74, 76 

 Phenothiazines, 14 

 Phenylalanine derivatives, toxic effects, 



67 

 Phenylketonuria, 67 

 Phosphatase activity in calcification, 15 



changes in autolysis, 98 

 Phosphatidic acid, 24 

 Phospholipids 



biosynthesis, 24 



synthesis, impairment in copper de- 

 ficiency, 105 

 Phosphoproteins, phosphorylation, 14 

 Phosphorus excretion in shock, 133 

 Phosphorylation, oxidative, effects of in- 

 jury, 53 

 Plasma globulins, abnormal, 46 

 Poisons 



anti-metabolic action, 72 



exogenous, 63 



respiratory, 57 

 Polymorphs, migration in inflammation, 



123 

 Polysaccharides in shock, 126, 137, 138 

 Pompe's disease, 33 

 Potassium, cellular, 7, 9, 10 

 Promethazine, protective action against 



carbon tetrachloride poisoning, 74, 76 

 Proteases, activation by injury, 115 

 Proteins 



action of hormones on, 42 



disturbances in damaged cell, 40 



in inflammation, 114 

 lipotropic action, 19 

 of normal cell, 36-48 



