Index 



147 



synthesis, role of ribonucleic acid, 38 

 role of vitamin B r ,, 39 

 Pyrogens, polysaccharide, 126, 127 



R 



Respiration, effects of injury, 53 

 Respiratory poisons, 57 

 Reticuloendothelial system in shock, 138 

 Riboflavin, effects of deficiency, 60 

 Ribonuclease release in autolysis, 98 

 Ribonucleic acid, 36 



control of protein synthesis, 38 



decrease in autolysis, 98 



effect of carbon tetrachloride on, 44 



soluble, 39 



synthesis, 51 



Sclerosis, multiple, 104 



Selenium factor and liver necrosis, 84 



Serine, 102 



Serotonin, role in inflammation, 112 



Shock, 131-140 



adrenocortical effects, 132 



bacterial products in, 136 



chemistry, 134 



endotoxins in, 126, 129, 136, 137' 



haemorrhagic, effect on myocardial 

 cell, 91, 93 



reticulo-endothelial system, 138 



toxic tissue products, 138 

 Sodium exchange, 8, 10 



pump, 8 



uptake of injured cells, 7, 9 

 Sphingomyelin, 27, 102, 103 

 Stress reaction, 129, 131 

 Strophanthin, effect on ionic movements, 



11 

 Succinic dehydrogenase, cardiac, 89 

 Sulphaguanidine, protective action 



against carbon tetrachloride, 74 

 Sulphur excretion in shock, 133 

 Swayback, 104, 105 



Tetanus toxin, anti-metabolic action, 80 

 Tetrabutylammonium, effect on ionic 

 movements, 11 



Thiamine, effects of deficiency, 59 

 Thioacetamide, anti-metabolic action, 76 

 Thymidine 5'phosphate, 37 

 Thymidylate, 37 



Thyrotoxicosis, metabolic effects, 95 

 Thyroxin, anti-metabolic action, 73 

 Tissue, toxic products in shock, 138 

 ^-Tocopherol deficiency and liver necro- 

 sis, 84 

 Toxic substances, anti-metabolic action, 



72 

 Transmethylation, 19 

 Tricarboxylic acid cycle, 52, 54, 72 

 Triethyl tin sulphate, anti-metabolic ac- 

 tion, 79 

 Triglyceride, 26 

 Triphosphopyridine nucleotide, effects 



of deficiency, 65 

 Typhimurium toxin, anti-metabolic ac- 

 tion, 80 



u 



Uridine triphosphate, 61 



Vacuolation, 5, 97 



Vasoconstrictor amines in shock, 135 

 Vasodilator amines in shock, 135 

 Vasodepressor material in shock, 136, 140 

 Vaso-excitor material in shock, 136 

 Ventricular fibrillation, effect on myo- 

 cardial metabolism, 91 

 Vitamin B 10 



effects of deficiency, 64 



role in protein synthesis, 39 

 deficiency states and respiratory en- 

 zymes, 59 

 E, effect of deficiency on liver cells, 13, 



14,84 

 K therapy and kernicterus, 61 



w 



Wallerian degeneration of peripheral 

 nerves, 102 



Water 



accumulation in injured cell, 5 

 exclusion from normal cell, 6 



