developmental instructions (growth regulation by nutrients in cultured plant 

 cells, role of light in plant and animal development). 



In his postscript A. Lang states that the general trend of the Symposium 

 pointed away from direct applications of the Jacob-Monod model to develop- 

 mental problems. The very first reactions to the developmental effectors 

 characteristic of higher organisms (particularly hormones) seem always to 

 occur at the level of membranes or protein receptors, not at the level of the 

 chromosomes. Experiments on Fucus eggs also implicate the cell surface in 

 the primary response to various effectors. 



The discussions held at the Symposium are not recorded, although Lang 

 repeatedly refers to them in his postscript. The book is well produced and is 

 concluded by author and subject indexes. 



42 BIOLOGY OF AMPHIBIAN TUMORS 



1969 

 Editor: M. Mizell Springer- Verlag 



Recent Results in Cancer Research Berlin - Heidelberg - New York 



Special Supplement Price: DM 86. — ; $ 24. — 



484 pp., 186 figs. 



Contributors: G. D. Abrams (Ann Arbor, Mich.), M. Balls (Norwich), V. V. Brunst 

 (Buffalo, N.Y.). B. R. Burmester (East Lansing, Mich.). H. F. Clark (Philadelphia, Pa.), 

 N. Cohen (Rochester, N.Y.), E. L. Cooper (Los Angeles, Calif.), C. J. Dawe (Bethesda, Md.), 

 L. E. DeLanney (Ithaca, N.Y.), M. A. DiBerardino (Philadelphia, Pa.), W. R. Duryee 

 (Washington, D.C.). M. A. Fink (Bethesda, Md.), J. J. Freed (Philadelphia, Pa.), L. Gallien 

 (Paris), P. Gerber (Bethesda, Md.), B. C. Giovanella (Madison, Wis.), A. Granoff (Memphis, 

 Tenn.), Ph. Grant (Eugene, Ore.), M. Green (St. Louis, Mo.), A. Greene (Camden, N.J.), 

 K. Habel (La Jolla, Calif.), R. R. Humphrey (Bloomington, Ind.j, J. M. Kirkwood (New York, 

 N.Y.), D. W. Legler (Birmingham, Ala.), V. G. Leone (Milan), Ph. D. Lunger (Newark, 

 Dela.), D. Malamud (Philadelphia. Pa.), R. A. Manaker (Bethesda, Md.). R. G. McKinnell 

 (New Orleans, La.), M. Mizell (New Orleans, La.). J. A. Moore (Riverside, Calif.), D. J. 

 Mulcare (Ann Arbor, Mich.), G. W. Nace (Ann Arbor, Mich.). B. Pollara (Minneapolis, 

 Minn.), K. E. Rafferty Jr. (Baltimore, Md.), D. J. Richey (Athens, Ga.), B. Roizman (Chicago, 

 111.), L. N. Ruben (Portland, Ore.), S. S. Schochet, Jr. (Washington, D.C.). I. Toplin (May- 

 wood. N.J.), K. S. Tweedell (Notre Dame. Ind.). E. P. Volpe (New Orleans, La.), K. Wolf 

 (Kearneysville. W.Va.) 



This book contains the papers read at a Symposium held at Tulane Univer- 

 sity. New Orleans, in October 1968. It is reviewed here because its scope 

 is much broader than the title would suggest. It contains a considerable amount 

 of material of general interest to developmental biologists working on 

 amphibian material. 



Almost all of the 43 papers report on recent original research. We will 

 mention only those subjects that are of more specific interest to our readers: 

 (1) population genetics of Rana pipiens (Moore), (2) mutations in Pleuro- 

 deles (GalHen), (3) nucleo-cortical interactions in the blastula (Grant), (4) 

 mass culture of amphibian cells (Rafferty), (5) cell lines from haploid and 

 diploid embryos (Freed et aL), (6) several papers on the immunology of 

 amphibians (Cooper, Volpe et aL, Cohen, Legler et aL, Pollara et aL), 

 (7) organ culture of amphibian tissues (Balls), (8) development of genetically 

 defined strains of amphibians (Nace), and (9) diseases of frogs kept in the 

 laboratory (Abrams). 



The book is well produced and well illustrated. Publication has been very 

 rapid, but a great drawback for the use of the book as a work of reference 

 is the absence of indexes. 



31 



