a 



tlon and their control. The volumes certainly are bv far t-h^ 

 most comprehensive source available on the subject. The malorltv 

 of the contributors are North-American, but there are also con 

 tributions from England, Australia, and Israel 



We cannot review the volume in detail here, but must restrict 

 ourselves to mentioning the main features. Most of the material 

 of course relates to the mammals and man. In volume 1 the main 

 sections are those on comparative hematology (2 chapters one of 

 them an extended review of hemocytopoiesis in insects) on the 

 histophysiology of bone marrow (2 chs.), on the hemopoietic stem 

 cell (5 chs.), and on the red blood cell (21 chs.). in volume 2 

 we find a section on leukocytic granulocytes, lymphocytes, and 

 monocytes (22 chs.), and one on platelets (3 chs.). Throughout 

 the treatise equal attention is devoted to morphology-, ultra- 

 structure, physiology, and biochemistry. Various authors discuss 

 the kinetics and possible models of hematopoiesis . Fetal erythro- 

 poiesis and fetal hemoglobins are also treated. 



The books are well printed and profusely illustrated. The re- 

 production of the numerous electron micrographs is reasonable to 

 good. The absence of author indexes is to be regretted, and the 

 subject indexes could have been more detailed. 



Monographs 



50. 



P.BIBERFELD. 1971. MORPHOGENES^IS IN BLOOD LYMPHOCYTES STIMULATED 



WITH PHYTOHAEMAGGLUTININ (PHA), a light and electron microscopic 



study 



Munksgaard, Copenhagen. Acta Pathol .Microbiol .Scand. Sect .A, 



Supplement No. 223. 70 pp., 73 figs., 3 tabs. 



Comprehensive study correlating size and cytochemical and ul- 

 trastructural features of lymphocytes being transformed into 

 blastoid cells by PHA; good photo- and electron micrographs. 



51. 



I.L.CAMERON, G.M.PADILLA and A.M.ZIMMERMAN, eds. 1971. 

 DEVELOPMENTAL ASPECTS OF THE CELL CYCLE 



Academic Press, New York, etc. Cell Biology: a series of mono- 

 graphs. XII, 387 pp., 87 figs., 27 tabs., author and subject in- 

 dexes. $ 19.50, £ 9.10 



Contributors: Bleyman, Buell, Cameron, Corff, Cosgrove, Fahey, 

 Flickinger, Jeter, Lane, Lasher, McCulloch, Nelson, Padilla, 

 Rustad, Sox, Till, Turkington, Yuyama 



In recent years much more has become known of the relationship 

 (and the possible antagonism) between cell proliferation and 

 cell differentiation. It is now known in several instances that 

 a cell's ability to differentiate or transform is related to its 

 position in the cell cycle. Moreover, the rate and nature of 

 gene transcription in embryonic cells seems to depend on the 

 length of the cell cycle, and this differs from one region to 

 another. 



Problems from this general area are treated in the present 

 book in 13 short reviews by 1.8 North-American authors. A broad 

 range of organisms is covered: Trypanosomatids , Naegleria, Te- 

 trahymena. Hydra, sea urchin and amphibian embryos, and various 

 tissues and cells of higher vertebrates (among them cartilage, 

 muscle, lens, mammary gland, blood and lymphoid cells, and male 

 germ cells). One contribution, dealing with initial stages of he- 

 mopoiesis in the mouse, is somewhat outside the scope of the book 



31 



