1969. The conference was attended by a vast number of participants from all over the world, 

 and appears to have been very well organized. The participants were not only teratologists and 

 clinicians, but also developmental biologists, which made for a very broad scope of approach. 

 The discussions held at the Conference are not recorded. 



After the opening session the conference started with a Symposium entitled "Developmental 

 Biology 1969". This was in two parts: 1) The biochemistry of differentiation (papers by 

 Church, Hess, Papaconstantinou, Stern and Schimke), and 2) Control mechanisms in develop- 

 ment (papers by Siniscalco, David, Hay, L. Weiss and Abercrombie). Next came five sessions, 

 respectively devoted to the uterine milieu and early embryo (3 papers), early embryo — 

 exogenous factors (3), birth defects in man (10), prospective studies — a progress report (3), 

 and management — present and future (6). 



Next followed a number of concurrent discussion and free paper sessions, which are repre- 

 sented in the book by brief summaries written by the session chairmen. Among these the 

 following may be mentioned: Molecular genetics (Ursprung); Mechanisms of teratogenesis 

 (Wilson); and The embryology of malformations (Langman). The Conference was closed by a 

 summing-up session in which six participants spoke. One of them was C. L. Markert, who 

 talked about the contributions of developmental biology to the understanding of congenital 

 malformations. 



The book is beautifully printed and very well illustrated. It has a list of authors, a complete 

 list of participants, and subject and author indexes. The latter only gives the authors of 

 invited papers; it it a pity that the authors of free papers were not included. It is not clear why 

 a book with a large prospective market should be so expensive. 



35 



METHODS FOR TERATOLOGICAL STUDIES IN EXPERIMENTAL ANIMALS AND MAN. 1969. 



Edited by H. NISHIMURA and J. R. MILLER 



Igaku Shoin, Tokyo; Pitman Medical, London. 328 pp., 110 figs., 62 tabs., subject index. SBN 



272 75994 5. 210 s. 



Contributors of lectures: Asling, Brent, Dempsey, Fraser, Froehlich, Hayashi, Makino, J. R. 

 Miller, R. W. Miller, Murakami, Nomura, Sever, Stevenson, Takano, Uno, Warkany, Wilson 



This book contains the proceedings of the Second International Workshop in Teratology held 

 in Kyoto in April, 1968. Apart from the contributors listed above it was attended by a 

 number of observers from all over the world, who took part in the discussions. 



The nature of the subject matter in the book is threefold, viz. 17 lectures, 6 "demonstrations", 

 and 11 "exhibitions". The lectures deal with a variety of subjects and material (man, other 

 primates, and laboratory mammals), Several are comparative in scope, placing human data 

 next to those on animals. At least nine of them are of direct interest to experimental terato- 

 logists. All are in English and about half of them are followed by brief discussions. 



Most "demonstrations" cover about five pages and are devoted to various methodological, 

 technical, and diagnostic aspects of teratology. The longest one (18 pp.) is an interesting 

 comparison of normal and abnormal gross development in man and laboratory mammals by 

 H. Nishimura and H. Yamamura. The "exhibitions" are brief outlines of exhibits shown during 

 the workshop; several of these extend material presented in the lectures. 



Apart from the bibliographies of the lectures there is a selected classified list of books and 

 review articles on embryology and teratology. The book has a good subject index but no 

 author index or list of participants. It is well printed and well illustrated. No attempt has 

 been made to correct the English of the non-Anglo-American speakers. The price of the book 

 seems excessive, perhaps due to the use of heavy-quality glossy paper. 



36 



RADIATION BIOLOGY OF THE FETAL AND JUVENILE MAMMAL. 1969. Edited by M. R. 



SIKOV and D. D. MAHLUM 



U.S. Atomic Energy Commission, Oak Ridge, Tenn. AEC Symposium Series vol. 17. 1040 pp., 



391 figs., 184 tabs., subject index. $ 3.00 (paper) 



This large volume contains the proceedings of a Symposium held in Richland, Wash, in May 

 1969. It was attended by about 200 scientists from the U.S.A. and eleven other countries. 



338 



