(12 pp.), 3) an extensive chapter on the differentiation of the trophoblasi 

 (92 pp.). an<i ^) '^ chapter on chorion-embryonic relationships (19 pp.). 

 Much of the discussion is based on the author's own research and that of 

 his associates. 



The third of the chapters listed above is subdivided into five sections as 

 follows: section A deals with morphological observations (implantation, 

 lacuna formation, previllous and villous trophoblast; section B describes the 

 formation of auxiliary placental structures (primary mesoderm formation, 

 angiogenesis, and amniogenesis); section C deals with the trophoblast in 

 organ culture (based on the work of T.-W. Tao); section D treats the 

 histochemistry of the developing trophoblast, while section E discusses the 

 physiological significance of these findings. 



The rest of the book deals with the pathology of the trophoblast at various 

 stages. The book is illustrated profusely, mainly with very fine gross and 

 microscopic photographs and reconstructions. Much of the illustrative material 

 originates from the Carnegie Department of Embryology. The book is very 

 well produced, has a bibliography of more than 150 titles, and is concluded 

 by a detailed subject index. 



47 PRENATAL DETERMINANTS OF BEHAVIOUR 



1969 

 By J. M. Joffe Pergamon Press 



Intern. Ser. Monogr. Oxford etc. 



Exper. Psychol., vol. 7 Price: £ 5.0.0; $ 13.— 



366 pp., 19 figs., 52 tbs. 



No sharp borderline can be drawn between experimental teratology and 

 the effects of prenatal treatments on postnatal behaviour. This monograph 

 deals with effects that every experimental teratologist is liable to encounter 

 during his experiments. It is a review and critical discussion of evidence on 

 the effects on postnatal behaviour of a variety of agents, including X-rays, 

 drugs, hormones, nutrition, and stress situations. Two features of the book 

 are of particular value to teratologists: the emphasis throughout on the 

 methodology of this type of work rather than on the substantive findings, 

 and the stress put on the interaction of environmental factors with the 

 hereditary constitution of the experimental animal. Most of the book deals 

 with the results of experiments on mammals. Three of the 11 chapters deal 

 with the human subject. 



The book is well produced and illustrated almost exclusively with graphical 

 material. It has a 21 -page bibliography, a name index, and a detailed subject 

 index. 



48 TERATOLOGY OF THE CENTRAL NERVOUS SYSTEM 

 Induced and spontaneous malformations of laboratory, 

 agricultural and domestic mammals 

 1968 

 By H. Kalter The University of Chicago Press 



483 pp., 20 fiqs., 3 tbs. Chicago - London 



Price: 157 s.; $ 17.50 



This thorough work is essentially compilatory in nature; it is written by 

 a long-standing expert in the field. The exclusion of the human species, 

 though it seems justified from the size of the book as it is, is nowhere argued 

 explicitly. However, the non-human mammals are treated exhaustively. 



333 



