annual meeting of the Tissue Culture Association (June 4 — 7). The idea 

 behind the Symposium was the evolution of defense mechanisms. An attempt 

 was made to bring together information bearing on some primitive anatomical 

 and physiological attributes of lower organisms which contribute to their 

 defense and survival. Important mechanisms involved are cellular aggregation 

 and cell recognition. 



The 15 research papers are grouped in three sections, respectively dealing 

 with aspects of aggregation and differentiation, with insect cell cultures, and 

 with primitive mechanisms of resistance to infection. The last section is of 

 no direct interest to developmental biologists. The first section contains papers 

 on plant cells (Sussex and Clutter), sponge cells (Moscona), and Hydra 

 (Campbell; Lenhoff; Haynes et al.). The second section contains papers by 

 Fox et al, Marks et al, Doyle and Laufer, and Grace. The first of these is 

 particularly interesting because it focuses largely on the biochemical different- 

 iation of embryonic Drosophila cells in culture. 



The book is beautifully produced and illustrated. It is concluded by a 

 combined author and subject index. 



57 LES INTERACTIONS TISSULAIRES 



AU COURS DE L'ORGANOGENESE 

 1969 

 Editor: E. Wolff Dunod 



244 pp., 100 figs.. 9 tbs., 16 pis. Paris 



Price: £ 6.6.6 



Contributors: Benoit (Nogent-sur-Marne), Croisille (Paris). Dameron (Paris), Le Douarin 

 (Nantes), Marin (Paris), Schowing (Nogent-sur-Marne), Sengel (Grenoble), Sigot (Nogent- 

 sur-Marne), Tiedemann (Berlin), Wolff (Paris). 



This series of papers is based on a series of seminars given at the College 

 de France during 1967. In almost all of them the emphasis was on the greater 

 or lesser degree of specificity of inductive interactions encountered in various 

 systems. This emphasis seems justified in order to counterbalance the 

 frequently expressed idea that inductive interactions tend to be aspecific. 

 The papers give so much background information that they are understand- 

 able for students and non-specialists. 



Except for H. Tiedemann, all authors are or have been closely associated 

 with the laboratory of Prof. Wolff, and all are working on aspects of avian 

 organogenesis. The following systems are considered, among others: kidney, 

 liver, skin and feathers, neurocranium, lung, and stomach. Immunological 

 aspects of inductive interaction are discussed in a chapter by Y. Croisille. 

 H. Tiedemann considers biochemical aspects of tissue interactions in the 

 early amphibian embryo. E. Wolff has contributed a brief introduction and 

 a concluding chapter, both lucidly written, as well as a chapter on general 

 principles of determination, in which he devotes much attention to the recent 

 experiments of Hadorn and his group on insect imaginal disc material cultured 

 in vivo. 



The book is well produced and profusely illustrated. It is concluded by 

 an author index. The price is unfortunately prohibitive, particularly for 

 students. 



338 



