Dissertations 



50. 



W.R.BATTINICH. 1972. THE EFFECTS OF THALIDOMIDE ON EARLY LIMB 



DEVELOPMENT IN RHESUS MONKEY (Macaca mulatta) 



Ph.D. thesis, Univ. of Calif., Berkeley. IX, 80 pp. (mimeographed, 



photomicrographs and drawings) 



Careful morphological study of forelimb development based on 

 19 embryos from treated mothers; Streeter's horizons used for 

 stageing; interpretation of results in terms of damage to pros- 

 pective limb fields and regulation of defects; extensive litera- 

 ture discussion. 



51. 



S.CROS-BONNEMAISON. 1970. CONTRIBUTION A L ' ETUDE EXPERIMENTALE 

 DE L'ACTIVITE TOXIQUE ET TERATOGENE DU DIMETHYLSULFOXYDE A 

 L'EGARD DE L « EMBRYON DE POULET 



Ph.D. thesis, Toulouse. XVIII, 147 pp. (mimeographed), 17 photo- 

 graphic pis., 31 figs., 29 tabs. 



Thorough study with emphasis on limb malformations; biochem- 

 ical action on serum proteins; distribution of DMSO in limb bud 

 mesenchyme; action of DMSO analogues. 



52. 



M.R.DANDRIEU. 1972. DE INVLOED VAN ANTI-BOVINE-ALPHA- CRYSTAL- 

 LINE OP DE ONTWIKKELING VAN HET KONIJNEOOG (The influence of 

 anti-bovine-alpha crystallin on the development of the rabbit 

 eye) 



M.D. thesis, Free Univ., Amsterdam. 101 pp., 24 figs. English 

 discussion (3 PP • ) and summary (2 pp.) 



Thorough study based on modern concepts and techniques of 

 immunology; improved immunization technique; cross reactions 

 between ocular and extra-ocular tissue antigens; placental pas- 

 sage of antibody; main results (obtained on young of three 

 months old): morphological and clinical anomalies of lens and 

 retina, pupillary rigidity, skin lesions. 



53. 



A.HERZOG. 1971. EMBRYONALE ENTWICKLUNGSSTORUNGEN DES ZENTRAL- 



NERVENSYSTEMS BEIM RIND 



Habilitation-dissertation, Giessen. Giessener Beitrage zur Erb- 



pathol. und Zuchthygiene, Sonderheft 2. X,582 pp., 249 figs., 



40 tabs. 



Study based on the evaluation of 1783 abnormal calves, of 

 which almost 25% had CNS malformations; encompasses all the 

 known and many new CNS malformations; morphological and histol- 

 ogical descriptions; comparison with similar anomalies in other 

 domestic animals; literature discussions with respect to tera- 

 togenesis and etiology; fetal haemorrhages and congenital neo- 

 plasia in the CNS; correlations with other organ systems; illus- 

 trated with photographs and micrographs; bibliography of more 

 than 700 titles. 



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