54. 



G.J.SCHADE. 1973. DE EMBRYONALE SCHEDELONTWIKKELING BIJ OPWEK- 

 KING VAN EEM GESPLETEN VSRHEMELTE, een experimenteel onderzoek 

 bij de muis (Growth and development of the skull after experi- 

 mental Induction of cleft palate in mouse embryos) 

 M.D. thesis, Univ. of Amsterdam. XII, 114 pp., 37 figs., 11 tabs. 

 English summary (4 pp.) 



Description of normal palate development in 9-19-day mouse 

 embryos; median cleft palate induced by amnion puncture around 

 l4g days; palate development in cleft embryos (15-19 days); 

 study of ossification sequence and skull growth (27 dimensions) 

 in normal and cleft embryos (16-19 days); statistical analysis; 

 good photographs and micrographs. 



Symposium reports 



55. 



M.A.KLINGBERG, A . ABRAMOVICI , and J.CHEMKE, eds. 1972. DRUGS AND 



FETAL DEVELOPMENT 



Plenum Press, New York, etc. Adv. in Exp. Med. and Biol. Vol.27'. 



XIV, 559 pp., 151 figs., 7 pis., 138 tabs., subject index. $ 31.50 



This book contains the 44 papers presented at the first Inter- 

 national Symposium on the effects of prolonged drug usage on 

 fetal development, held in Israel in September, 1971. The range 

 of topics covered is extremely broad. An interesting feature of 

 the book is that many authors seem to belong to the younger gen- 

 eration whose work is just becoming generally known. About half 

 of the papers will be mainly of value to clinicians interested 

 in drug effects, but at least 20 are of interest to teratologists 

 generally . 



Most of the papers in question report on recent research in- 

 volving laboratory and domestic mammals and birds. Except drugs 

 in the strict sense, hormones, vitamins, and minerals were used 

 in some studies. Morphological studies are in the majority, bio- 

 chemical work being reported in half a dozen papers, and ultra- 

 structural work in none. Some of the papers are very short. The 

 discussions are not recorded. 



The book is produced in offset print at a rather high price. 

 The photographic illustrations are well reproduced. The index 

 could have been more extensive. 



DEVELOPMENTAL PATHOLOGY, CANCER (see also 47,49,74,80,98,107, 



110,112) 



Treatises 



56. 



N.S.ASSALI, ed. 1972. PATHOPHYSIOLOGY OF GESTATION Vol.2, Fetal- 



placental disorders 



Academic Press, New York, etc. XVI, 357 pp., 67 figs., 15 tabs., 



author and subject indexes. $ 25.00 



Contents: 1. Disorders of placental transfer (Longo); 2. Dis- 

 orders of placental endocrine functions (Simmer); 3« Disorders 

 of amniotic fluid (Liley); 4. Genetic disorders affecting 

 growth and development (Sparkes and Crandall); 5« Environmen- 

 tal effects on development - teratology (Wilson) 



This is the second volume of a three-volume multi-author trea- 

 tise. Vol.1 is entitled Maternal Disorders, and vol.3 Fetal and 

 Neonatal Disorders. They will not be reviewed here. The aim of 



208 



