mal or dystrophic muscle tissue of mammals, the chick, and the 

 lizard. Each group of two or three papers is followed by 2-k 

 pages of highly interesting discussion, with separate references. 

 The book is very well produced and profusely illustrated, most- 

 ly with very good light and electron micrographs. Unfortunately 

 the price must be considered excessive. 



93. 



R.J.GOSS, ed. 1972. REGULATION OF ORGAN AND TISSUE GROWTH 

 Academic Press, New York, etc. XIV, 365 pp., 91 figs., 35 tabs., 

 author and subject indexes. $ 20.00 



This book is based on an ail-American Symposium held in Phila- 

 delphia in December, 1971. Most of the 23 contributors work in 

 bio-medical institutions and departments. The Symposium was 

 meant to encourage the exchange of ideas among people whose 

 paths do not ordinarily cross. It is therefore a pity that the 

 discussions are not recorded; nevertheless, the book is valuable 

 for the breadth of its coverage. 



There are introductory chapters on theories of growth regula- 

 tion (Goss) and on growth and renewal (Leblond). In the remain- 

 ing 16 chapters a great variety of mammalian organs and tissues 

 pass in revue, most with emphasis on postnatal growth: brain, 

 muscle, heart, skeleton, blood, lymphatic system, liver, kidney, 

 lung, and several more. Each chapter is a review by a specialist 

 of recent work, seldom more than 10 years old, and together they 

 constitute an excellent overview of the field. The multitude of 

 regulatory factors that emerge should be an incitement to much 

 more investigation. 



The book is well produced and illustrated. 



CELLULAR DEVELOPMENTAL BIOLOGY (incl. cell culture, cytochemis- 

 try) (see also 16,68,83,113,119) 

 Treatises 



94. 



R.BASERGA, ed. 1971. THE CELL CYCLE AND CANCER 



M.Dekker, New York. The Biochemistry of Disease, vol.1. 



XII, 481 pp., 78 figs., 26 tabs., author and subject indexes. 



$ 29.50 



This treatise, written by an international team of experts, 

 is primarily meant for workers using mammalian material in basic 

 bio-medical research. However, the cell cycle is so basic to all 

 biological research, and the book is so well-balanced and au- 

 thoritative that we briefly review it as a service to our 

 readers. It consists of a series of concise but well-organized 

 and clearly written reviews which cover nearly every aspect of 

 the subject in a thoroughly modern fashion. Literature data are 

 often condensed into very useful tables, and extensive bibliog- 

 raphies are provided. The chapters are linked together singly or 

 in groups by thoughtful introductions by the editor. 



We restrict ourselves to enumerating the subjects of all chap- 

 ters (except the two that deal specifically with cancer cells): 

 proliferative cycle of mammalian cells (Lipkin); proliferation 

 and maturation of hemopoietic cells (Blackett); critical evalua- 

 tion of the FLM method (Mendelsohn and Takahashi); differentia- 

 tion and the cell cycle (Malamud); effects of hormones on the 

 cell cycle (Epifanova); biochemistry of growth initiation in 

 resting cells (Cooper); cytophotometry and histochemistry of the 

 cell cycle (Vendrely); biochemistry of Gl and S phases (Mueller); 



221 



