DEVELOPMENTAL BIOCHEMISTRY AND MOLECULAR BIOLOGY (see also 2,16, 

 17,22,45,73,74,80,83,92,94,98,99,100,115,118,119,123,125,135) 



Monographs 



101. 



L.S.MILMAN and Yu . G . YUROWITZKY . 1973. REGULATION OF GLYCOLYSIS 



IN THE EARLY DEVELOPMENT OF FISH EMBRYOS 



Karger, Basel, etc. Monographs in Developmental Biology vol.6. 



VI, 106 pp., 23 figs., 25 tabs. Sfr. 46.00, $ 12.90, £ 5.40, 



DM 39.00 



Contents: 1. Glycolysis in early embryogenesis; 2. Co-ordina- 

 tive changes in activities of glycolytic enzymes during ooge- 

 nesis; 3. Peculiarities of oocyte metabolism; 4. The role of 

 phosphorylase in the control of hexose monophosphate levels; 

 5. Enzymes of hexosomonophosphate metabolism; 6. Control of 

 the fructose-1 , 6-diphosphate level in the developing embryo; 

 7. Factors controlling the conversion of triosephosphates to 

 lactate in the loach embryo; Appendix: Allosteric regulation 

 of enzyme activity 



The authors of this monograph have been active investigators 

 in this field since about 1965 and have produced a long series 

 of joint papers written mostly in Russian. The book reviews 

 this work, carried out on eggs and embryos of the loach, Mis- 

 gurnus fossilis, in connection with the work of many others on 

 eggs and embryos of fish and other animals. 



The book is largely characterized by the table of contents. 

 Particular attention is devoted to a comparison of the metabo- 

 lism of oocytes and embryos, since in the loach the Embden- 

 Meyerhof pathway emerges during the phase of rapid growth of 

 the oocyte. The period of early embryogenesis considered rough- 

 ly extends till the end of gastrulation. The stability and 

 self-adjustment of metabolic systems during development by 

 feedback control in several controlling steps is extensively 

 discussed. 



The book is well produced and has a 13-page bibliography that 

 is up-to-date until about 1969/70. There are no indexes. 



102. 



H.URSPRUNG, ed. 1972. NUCLEIC ACID HYBRIDIZATION IN THE STUDY 

 OF CELL DIFFERENTIATION 



Springer, Berlin, etc. Results and problems in cell differentia- 

 tion vol.3. XI, 76 pp., 29 figs., 12 tabs., DM 36.00, $ 11.50 



This volume brings together six articles by investigators ac- 

 tive in developmental and cell biology who use nucleic acid hy- 

 bridization as a tool in their research. Contrary to what the 

 title suggests, only the first two papers have a direct bearing 

 on cell differentiation, while the others are mainly concerned 

 with the wider area of gene regulation at the biochemical level. 

 Not all papers are equally up-to-date. 



Tobler briefly reviews the problem of the genetic identity of 

 different cell types, basing himself on data from a variety of 

 organisms. Church and Brown discuss the tissue specificity of 

 genetic transcription, mainly on the basis of their own work on 

 mouse embryos (a welcome complement to the numerous studies on 

 sea urchins and amphibians). The paper by Purdom, Williamson, 

 and Birnstiel is largely methodological in character. Hybridiza- 

 tion of nucleic acids to chromatin and to chromosomes, respec- 

 tively, is discussed by Kim and by Steffensen and Wimber. Final- 



225 



