DEVELOPMENTAL PATHOLOGY, CANCER (see also 55,78) 



Monographs 



35 



G V SHERBET, ed. 1974. NEOPLASIA AND CELL DIFFERENTIATION 



Karger, Basel, etc. XIV ,411 pp., 47 figs., 7 tabs., subject index. Sfr. 140.00, $43.40, 



£20.30, DM 133.- 



Contributors: Auersperg, Burgess, Carlson, Collins, Easty, Finnegan, Gaillard, 



Lakshmi, Neyfakh, Sherbet, Sigot-Luizard, Simnett, Wolsky 



In recent years the possibility of interrelations between neoplasia and epigenetic 

 mechanisms acting in normal development is being increasingly stressed. This collection 

 of extensive reviews (most are ca. 30-50 pages long) is of interest to both cancer 

 researchers and developmental biologists, particularly as a work of reference. In this 

 connection the absence of an author index is to be regretted. 



The reviews are authoritative and well organized. Most cover the literature up to about 

 1970 a few up to 1972. Among the subjects covered are the following: nuclear 

 differentiation in normal and neoplastic development; molecular biology of embryonic 

 development; early events in regeneration; genome control in blastema ce Us; gene- 

 inhibiting chemicals and regeneration; the cell surface in morphogenesis; differentiation 

 of tumours in vitro; teratomas; embryonic-tumour cell association and cell interaction. 



The book is well produced but definitely too expensive. 



R 6 E.STEVENSON. 1973. THE FETUS AND NEWLY BORN INFANT, influences of the 

 prenatal environment n]6n 



Mosby, St. Louis. X,391 pp., 58 figs., 133 tabs., subject index. $ 31.80 



Contents: I. Prenatal immunologic influences (2 chs.); II. Prenatal chemical ■ inHuences 

 (chs on metabolic disturbances, and on drugs and hormones); III. Prenatal infections 

 (5 chs.); IV. Prenatal nutrition (2 chs.); V. Other influences (chs. on radiation, oxygen, 

 malignant diseases, and maternal age) 



Because of its systematic organization this book will be very useful as a Reference 

 source for clinicians and others interested in human development An important feature is 

 that the magnitudes of the environmental influences are quantified wherever possible 

 Placental abnormalities and inherited disorders of the fetus are not considered. The 

 treatment is to some extent selective, with emphasis on the most important and best- 



faV ? taJeVmSunt of literature is cited throughout the book. References more recent 

 than 1970 or '71 and non-English titles are rare. Numerous literature data are brought 

 together in synoptic tables. 



The book is printed on glossy paper and well illustrated. 



Symposium reports 



E 7 V.D.PERRIN and M.J.FINEGOLD, eds. 1973. PATHOBIOLOGY OF DEVELOPMENT 



- or ontogeny revisited ciqtc 



Williams & Wilkins, Baltimore. XII,151 pp., 53 figs., 34 tabs., subject index. $ 19.75 



Contributors: Bolande, Brent, Epstein, Holtzer, Kretchmer, Landing, Mayne, Saxen, 

 Sever, Warkany, Wilson 



This book is the report of a symposium held by the American Association of 

 Pathologists and Bacteriologists in Cincinnati, Ohio some time during 1972 Of the 11 

 contnbuTors ten were North-Americans. The book is probably of most use to clinicians 



183 



