who want to update themselves on the subject. For experimental teratologists more 

 comprehensive sources are available. The discussions, which were apparently not edited, 

 are of limited use. 



All ten papers are reviews. Most arc well organized, some less so. Four have no more 

 than 4 l > pages of text. In short, the quality is uneven and the nature partly ephemeral. 



It is not clear why such a book should be produced so luxuriously and consequently at 

 too high a price for its value. 



38. 



L.TOMATIS, U.MOHR, and W.DAVIS, eds. 1973. TRANSPLACENTAL CARCINO- 

 GENESIS 



World Health Organization, Intern. Agency for Research on Cancer, Lyon. IARC Scient. 

 Publications No. 4. XVI, 181 pp., 98 figs., 43 tabs. £5.00, $12.00, Sw.fr. 40.00, 

 Fr.fr. 56.00 (paper) 



This book contains the papers read at a symposium held at Hannover, Germany in 

 1971. It was convened to review the most recent experimental results in transplacental 

 carcinogenesis in laboratory mammals, and to assess their significance in relation to a 

 possible carcinogenic risk for man. The 44 participants came from various Western- 

 European countries and the USA (with one participant from Japan). 



Almost all of the 20 papers are of direct or indirect interest to those who work on 

 teratogenesis in mammals. They range in length from four to 16 pages. Several papers 

 discuss the embryotoxic and teratogenic effects of particular carcinogens. Although the 

 nervous system seems to be most susceptible to transplacental carcinogenesis, tumours in 

 a variety of other organs are also described. Much attention is devoted to the possible 

 modes of action of the drugs concerned. 



The discussions held at the symposium are not recorded. There is a brief summary of a 

 general discussion at the end of the book. The book is well produced and well illustrated. 

 It has no indexes. 



REGENERATION, RENEWAL (see also 2,6 1,64) 



Dissertations 



39. 



W.VAN DER MEER-FIEGGEN. 1973. REGULATION OF CELL PROLIFERATION 



AND DIFFERENTIATION IN INTESTINAL EPITHELIUM 



M.D. thesis, Rotterdam. 72 pp., 15 figs., 17 tabs. 



Study of cell proliferation (3H-thymidine) and differentiation (microchemistry of 

 carboxyl esterase) in crypts and villi of the duodenum of conventional and germ-free rats 

 treated with low doses of X-irradiation; feedback regulation from villus to crypt; no 

 effect of partial resection of jejunum and ileum. 



Books of readings 



40. 



C.S.THORNTON and S.C.BROMLEY, eds. 1973. VERTEBRATE REGENERATION 

 Dowden, Hutchinson & Ross, Stroudsburg. Benchmark Papers in Biological Concepts, 

 Vol.2. XIV, 512 pp., 156 figs., 27 pis., 47 tabs., author citation index, subject index. 

 $25.00, £ 13.25 



This book contains 29 facsimile reprintings of seminal articles in the field of vertebrate 

 regeneration. The emphasis is on the amphibian limb, but there are also papers on the 

 amphibian lens, amphibian and reptilian tail, mammalian antler, and mammalian limb. 



184 



