CELLULAR DEVELOPMENTAL BIOLOGY (incl. cell culture, cytochemistry) (see also 



2,5,11,23,42,44,47,51,54,57) 



Textbooks 



58. 



J.M.ASHWORTH. 1973. CELL DIFFERENTIATION 



Chapman & Hall, London, 64 pp., 35 figs., 4 tabs., subject index. £ 0,90, $ 2.75 (paper) 



J.M.ASHWORTH. 1974. ZELLDIFFERENZIERUNG, aus dem Englischen ubersetzt 

 von H. Lorz 



Fischer, Stuttgart. VIII, 95 pp., 35 figs., 4 tabs., subject index. DM 8.80 (paper) 



This guide book is a selective but very competent survey of recent advances in animal 

 cell differentiation, mainly from the molecular-biological point of view. It will be most 

 useful to advanced students. The book is organized in two main sections. The first takes 

 the reductionist approach and looks at simple model systems such as phages, bacteria, 

 cellular slime molds, and tissue culture cells. The second section deals with the more 

 complex special systems most frequently used today; it has sections on chromosome 

 structure and function, RNA synthesis, protein synthesis, protein degradation, protein 

 modification, and intermediary metabolism. 



There are ca. 70 references cited in the text and an annotated list of books for further 

 reading. 



The German edition is well turned out, but unfortunately the translator obviously did 

 not know enough English. There are numerous outright mistakes, and often the meaning 

 of whole sentences is lost. In this form the text is in places almost useless and extremely 

 confusing. 



59. 



R.L.DAVIDSON. 1973. SOMATIC CELL HYBRIDIZATION: STUDIES ON GENETICS 



AND DEVELOPMENT 



Addison-Wesley, Reading, Mass. Addison-Wesley Module in Biology No. 3. 39 pp., 6 figs., 

 8 tabs. 



This is an admirably concise and well-organized survey of the applications of a method 

 which has rapidly become of basic significance to mammalian cell and developmental 

 genetics. It is well suited for a rapid orientation in this field. Of most direct interest to 

 developmental biologists is the 1 1-page section entitled Regulation of differentiation in 

 hybrid cells. It has subsections on pigment cells (suppression of a differentiated function; 

 effect of gene dosage), on kidney cells (reappearance of a differentiated function), on 

 glial and neuroblastoma cells, and on liver cells (induction of a differentiated function). 

 In connection with these results attention is devoted to the implications for the problem 

 of determination, and to the possible existence of diffusible gene regulator substances 

 which may be either suppressors or inducers. 



60. 



D.R.GARROD. 1973. CELLULAR DEVELOPMENT 



Chapman & Hall, London. 64 pp., 47 figs., subject index. £ 0.90, $ 2.75 (paper) 



D.R.GARROD. 1974. ZELLENTWICKLUNG; zellulare Interaktionen in der Embryonal- 



entwicklung, aus dem Englischen ubersetzt von D. Hess 



Fischer, Stuttgart. VIII, 95 pp., 47 figs., subject index. DM 8.80 (paper) 



This guide book, written for advanced students, is a highly selective but ably written 

 outline of recent to very recent advances and ideas in some areas of animal developmental 

 biology: pattern formation, cell movement and morphogenesis, and intercellular com- 



191 



