\ Sn mposium. 1 973. LOCOMOTION OF TISSUE CELLS 

 Elseviei Excerpta Medica North-Holland, Amsterdam, etc. Ciba Foundation Sym- 

 posium 14 (new series). VIII.381 pp., 130 figs., 12 tabs., index to contributors, subject 

 index. D.fl. 49.00, about US $ 1^.60 



Contributors Abercrombie, Allison, Berg, Bray, Bunge, Bushnell, Buultjens, Chang, 

 Curtis, De Petris, Dickerman, Dunn, Gail, Gelfand, Goldman, Gustafson, Harris, 

 Hopkins, Luduena, Middleton, MUler, Pollack, Porter, Raff, Spooner, Steinberg, Trink- 

 aus, Vasiliev, Wang, Wessells 



The mechanism of cell movement is of direct interest to developmental biologists, 

 particularly those interested in morphogenetic movements. This symposium, held in 1972 

 in London, was apparently the first international meeting on the locomotion of tissue 

 cells, as opposed to large rhizopod protozoa. There were 24 participants from various 

 European countries and the U.S.A., and the papers and discussions collectively represent 

 the latest state of the subject. The papers either review recent to very recent published 

 data, or report results unpublished in 1972, or both. 



Almost all papers will be read with great interest by developmental biologists. To- 

 gether they cover all aspects of the subject that are now known to be important: cell 

 surface movement and fluidity, intracellular actomyosin, microfilaments and micro- 

 tubules, cell adhesion, formation and behaviour of the various classes of processes put out 

 by cells-, contact inhibition of movement (of which a new interpretation is suggested), and 

 the roles of serotonin, acetylcholine, and calcium. 



All these are studied in a variety of cells in vitro and in vivo, including nerve cells and 

 cells in fish and sea urchin embryos. The discussions are particularly interesting and often 

 contain the newest material, complete with illustrations and references. There are two 

 lengthy general discussions dealing, among other things, with cell adhesion, directed cell 

 movement, and the role of the substrate. 



The book is beautifully produced and illustrated, at a reasonable price. 



67. 



E.KULONEN and J.PIKKARAINEN, eds. 1973. BIOLOGY OF FIBROBLAST 

 Academic Press, London, etc. XIV.689 pp., 229 figs., 89 tabs., author and subject in- 

 dexes. £ 12.60, $35.50 



The role of connective tissue and, more generally, of extracellular matrices in develop- 

 mental processes is becoming more and more evident. Though not dealing with develop- 

 ment only, this symposium contains much that will interest developmental biologists, 

 particularly those working on subjects like cell differentiation in vitro, wound healing, 

 and tissue regeneration. The symposium was held in Turku, Finland in August 1972. Most 

 of the participants came from various Western and Middle-European countries and the 

 U.S.A. 



Most of the 60 brief to medium-length papers report on and/or review recent results. 

 They touch on a great many aspects of fibroblast biology, but also on such subjects as 

 chondrogenesis, osteogenesis, matrix synthesis and metabolism, and the cell surface. 



The papers are grouped as follows: General (4 papers); Cytological aspects and dif- 

 ferentiation (14, of which at least 6 are of direct interest to developmental biologists); 

 Extracellular space and cell surface (9); Specific synthetic functions (17); and Inflamma- 

 tion, repair and fibrosis ( 1 6). 



The book is well produced and illustrated. 



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