This widely-used book has been out of print for some time. The second 

 edition is an unchanged reprinting of the first, to which a nine-page biblio- 

 graphical appendix has been added which brings the literature references on 

 anuran development up to date. The book also contains references to all normal 

 tables of both anuran and urodelan species published up till 1967, as well 

 as a comparative table of a number of important series of normal stages of 

 anuran species. 



Apart from experimental embryologists, zoologists and comparative anat- 

 omists will also find much useful information in the book, particularly in the 

 extensive descriptions of the development of organ systems from the neurula 

 stage till the end of metamorphosis. In addition, there are introductory chapters 

 dealing with the taxonomy and zoogeography of the genus Xenopus, and with 

 laboratory breeding and rearing methods. 



The ten original plates illustrating the external morphology of the 66 stages 

 are also reproduced in this edition. The book now has a pliable, unstainable 

 cover, which ensures easier use in the laboratory. 



31 THE MOLECULAR BASIS OF REGENERATION: ENZYMES 



1966 

 by A. J. Schmidt University of Illinois Press 



Illinois Monographs in Med, Sci. Urbana & London 



Vol. VI, No. 4 Price: $ 4.50 



78 pp.. 40 figs, 

 (paper-bound) 



This monograph is based to a large extent on original investigations of the 

 author, who has been one of the few who have devoted more than passing 

 attention to the role of enzymes in amphibian limb regeneration. The in- 

 formation available at present is critically examined, and compared wherever 

 possible with similar data on cutaneous wound-healing in higher vertebrates. 

 In view of the limited size and somewhat restricted approach of the monograph 

 its title seems rather pretentious. 



After a brief introduction and a discussion of the phases of limb regeneration, 

 the main part of the monograph discusses the data available on more than 20 

 different enzymes (10 hydrolases, 10 oxidoreductases, and 2 other enzymes). 

 Possible metabolic pathways and cycles in the blastema are extensively dis- 

 cussed. The role of lysosomes is pointed out. 



The bibliography covers 12 pages and is up-to-date until 1964. The il- 

 lustrations consist mostly of original photomicrographs. A chart is provided 

 of the intermediary metabolism of the glycolytic and tricarboxylic acid cycles. 

 There is a short alphabetical index. 



32 I FATTORI METAGENETICI ESOGENI NELLE 

 MALFORMAZIONI CONGENITE (ORO-MAXILLO-FACIALI) 



Teratogenesi sperimentale e riferimenti clinici 



(The exogeneous metagenetic factors in the congenital malformations of the 



mouth, jaws, and face: Experimental teratogenesis and clinical data) 



1966 

 by F. Vichi and others Ediz. Minerva Medica 



658 pp., 131 figs.. 34 tbs. Saluzzo 



(paper-bound) 



This very thorough collaborative treatise by six Italian specialists is concerned 

 mainly with teratogenic factors exogeneous to the maternal organism which act 

 on the morphogenesis of the mouth, jaws, and face in the mammalian embryo. 

 The term "metagenetic" in the title indicates that special consideration is given 

 to factors acting after fertilization of the egg. However, the "progenetic" 



286 



