(Milano), Ishikura (Bethesda, Md.), Kahan (Cambridge, Mass.), Korngold (New York, N.Y.), 

 Krim (New York, N.Y.), Lawley (ILondon), Mandel (Houston, Tex.), Marmur (New York, 

 N.Y.), Menozzi (Milano), Newton (Cambridge), Niu (Philadelphia, Pa.), Peacocke (Ox- 

 ford), Polli (Milano). Ranzi (Milano), Reichard (Uppsala), Richards (Bethesda, Md.), Riddle 

 (Waltham, Mass.), Runnstrom (Stockholm), Sachs (Rehovoth), Sadron (Strasbourg), San- 

 filippo (Milano), Shooter (London), Tanaka (Bethesda, Md.), Thomas (Baltimore, Md.), 

 Villa (Milano) 



The conference of which this volume constitutes the report was held in 

 Milan in September 1963. It had 69 participants, the majority of whom were 

 Italian. Eight came from the U.S.A., six from Great Britain, and ten from 

 various other countries. Of the 23 papers presented, 22 are in English and one 

 in French. Most of the papers are followed by brief discussions. The con- 

 cluding remarks are by S. Ranzi. 



Four aspects of the problem under consideration were covered in this con- 

 ference, viz. DNA structure, DNA synthesis, transfer of information to 

 proteins, and applications of these results to the study of embryonic devel- 

 opment. The applications are considered in the four last papers: 1 ) "Nouvelles 

 observations sur le role des acides nucleiques dans la morphogenese" (J. Bra- 

 chet, 28 pp.); 2) "In vitro studies on the regulation of normal cell differentiation 

 and neoplasia" (L. Sachs, 24 pp.); 3) "Genetic and epigenetic factors involved 

 in the early differentiation of the sea urchin egg" (J. Runnstrom, 10 pp.), and 

 4) "RNA-induced changes in cells and embryos" (M. C. Niu, 20 pp.). 



41 DEVELOPMENT OF THE LUNG 



1967 



Editors: A. V. S. de Reuck and R. Porter J. 6 A. Churchill Ltd. 



Ciba Foundation Symposium London 



424 pp., 134 figs., 13 tbs. Price: 65 s. 



Contributors: Avery (Baltimore, Md.), Bartels (Tiibingen), Clements (San Francisco), 

 Cook (New Haven, Conn.), Cross (London), Cunningham (Oxford), Dawes (Oxford), De- 

 jours (Paris), Hugh-Jones (London), Hughes (Bristol), Kylstra (Durham, N.C.), Longmuir 

 (Raleigh, N.C.), Metcalfe (Portland, Ore.), Pattle (Salisbury), Plank (Presov), Purves (Cam- 

 bridge), Rahn (Buffalo, N.Y.), Reid (London), Robin (Pittsburgh, Pa.), Rooth (Lund), Ross 

 (Portland, Ore.), Strang (London), Tizard (London), Weibel (Ziirich), West (London) 



This volume embodies the proceedings of a symposium held in London in 

 November 1965. Of its 25 participants, 11 came from England, 9 from the 

 U.S.A., and 5 from various European countries. The main topic was the 

 development of the mammalian lung. 



The 16 papers are grouped in five sections, entitled respectively: "Phy- 

 logeny of the lung" (4 papers); "Ontogeny of the lung" (3 papers and a general 

 discussion); "The gas/liquid interface" (2 papers and a general discussion); 

 "Intrauterine gas exchange" (4 papers and a general discussion); and "The 

 start of breathing" (3 papers). Each paper is followed by a verbatim report 

 of the ensuing discussion. Apart from the general discussions at the end of 

 each session there are five additional group discussions at the end of the book. 



The following papers seem to be of particular interest to embryologists: "The 

 embryology of the lung" (by L. Reid); "Postnatal growth of the lung and 

 pulmonary gas-exchange capacity" (by E. R. Weibel); "A morphological 

 contribution to the development of the human lung: observations in the non- 

 retracted lung" (by J. Plank); "Comparative properties of the lungs and the 

 placenta: a graphical analysis of placental gas exchange" (by B. B. Ross); 

 "The oxygen supply of the foetus" (by J. Metcalfe); "Carriage of oxygen in 

 the blood of the foetus" (by H. Bartels); "Oxygen consumption of the placenta 

 and foetal membranes in the sheep" (by G. S. Dawes); and "Pulmonary 

 circulation in the foetus and the newborn" (by G. S. Dawes). 



An important feature of both the symposium and the book is the amount 

 of time and space allotted to discussions. These provide a wealth of additional 



292 



