Monographs 

 45. 



H.BANKL. 1977. CONGENITAL MALFORMATIONS OF THE HEART AND GREAT VESSELS, 

 synopsis of pathology, embryology and natural history 



Urban & Schwarzenberg, Baltimore, etc. XII, 264 pp., 58 figs., 7 tabs., 

 subject index. DM 60.00, $ 24.50, £ 15.75 



This book is largely based on the personal analysis of 1000 malformations 

 by the author at his institute in Vienna. The first part occupies 34 pages 

 and consists of a description of the development of the heart and major 

 vessels based on a variety of sources and illustrated with very good line 

 drawings and diagrams. The rest of the book is a rigorously classified in- 

 ventory of some 50 malformations. Wherever appropriate, each section- con- 

 sists of the following parts: definition and classification of subtypes; 

 frequency and distribution by sex; embryology; pathological anatomy; hemo- 

 dynamic consequences; and life expectancy and causes of death. This part is 

 illustrated with excellent original line drawings, photographs and diagrams. 



The book is beautifully produced and has a bibliography of close to 800 

 titles, both old and recent, many of them in German and some in French. 



46. 



H.A.GATHMANN and R.D.MEYER, 1977. DER KLEEBLATTSCHADEL, ein Beitrag zur 



Morphogenese 



Springer, Berlin, etc. Sitzungsberichte der Heidelberger Akad. der Wissen- 



schaften. Math. -Naturwiss. Klasse, suppl.2. X,129 pp., 77 figs., 4 tabs., 



subject index. DM 48,00, $ 22.10 



Anatomical, histological and X-ray analysis of one original and six museum 

 specimens of human neonatal clover-leaf skulls; typology and terminology; 

 developmental interpretation invoking a "cartilage factor", a "vascular fac- 

 tor" and a "tension factor", very good photographs and line drawings, 



47. 



J.L.SCHARDEIN. 1976. DRUGS AS TERATOGENS 



CRC Press, Cleveland. VIII, 291 pp., 109 figs., 76 tabs., subject index. 



$ 57.50, E 33.60 



This book will be of eminent value to teratologists . It is very practical 

 in outlook and embryologists will find little in it that will interest them 

 specifically. 



The first three chapters (53 pages) deal practically and sensibly with 

 the principles of drug testing and the evaluation of teratogenic (and other) 

 effects, as well as the relevance of animal studies for man. The rest of the 

 book is devoted to discussions of more than 1,200 drugs classified into 27 

 groups according to pharmacological activity. They are restricted to chemi- 

 cals which are in use or intended for use as therapeutic agents. Mouse, rat 

 and rabbit are emphasised as test animals but other species are also con- 

 sidered, as well as, of course, the human. 



The data are drawn together in informative tables wherever possible. The 

 use of illustrations is incidental and the photographs are not very well 

 reproduced. All chapters have extensive bibliographies which are up to date 

 until 1975. 



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