insect development (Nothiger et al.), plant growth and development (Barlow), 

 and lens development (Clayton) . 



Most of the papers in this volume are high-quality, up-to-date reviews of 

 recent research by predominantly Anglo-Saxon authors. The first contribution 

 (Holtzer) is particularly important theoretically in that it discusses the 

 occurrence of multipotent versus bipotent stem cells in animals, coming out 

 strongly against the former. The nine authors not mentioned above deal with 

 such subjects as lymphocytes (1 paper), haemopoiesis (6), the epithelium (1) 

 and the intestine (1). 



It seems a pity that the discussions could not be included in the book be- 

 cause the interdisciplinary exchanges must have been fascinating to hear. 

 The book is well produced and illustrated. 



87. 



W.W.NICHOLS and D.G. MURPHY, eds . 1977. REGULATION OF CELL PROLIFERATION 



AND DIFFERENTIATION 



Plenum, New York, etc. Cellular Senescence and Somatic Cell Genetics 



Vol.1. XII, 204 pp., 54 figs., 9 tabs., subject index. Dfl.71.50 



The title of this volume is misleading in that it suggests a much broader 

 scope of the contents than is the case. Because the symposium was held as 

 far back as 1975 we only briefly mention it for those who may have missed 

 it. It suffices to say that the second half contains six papers on various 

 cellular and metabolic aspects of myogenesis in vitro by recognised author- 

 ities in the field: Holtzer, Konigsberg, Nameroff, Hauschka, Stockdale and 

 Strohman. 



88. 



S.B.OPPENHEIMER and others. 1978. CELLULAR ADHESION 



Amer . Soc. of Zoologists, Thousand Oaks, Calif. Amer . Zoologist Vol.18, 1. 



83 pp., 51 figs., 4 tabs. $ 7.00 (paper) 



Papers from an unidentified symposium; two papers deal, among other 

 things, with sea urchin eggs and embryo cells: Cell surface carbohydrates 

 in adhesion and migration (Oppenheimer , 11 pp.) and Fine structural analysis 

 of animal cell surfaces (Pollock, 45 pp.); a third paper is entitled Liquid- 

 tissue mechanics in amphibian gastrulation (Phillips, 13 pp.); the latter 

 two are well illustrated. 



89. 



G.F.SAUNDERS, ed . 1978. CELL DIFFERENTIATION AND NEOPLASIA 



Raven, New York. XX, 549 pp., 245 figs., 70 tabs., subject index and index to 



contributors. $ 51.35 



Contents (abridged): I. Stage of cellular differentiation in tumor cell 

 origin: i Germ cells (2 papers) , ii Tissue differentiation and oncogenesis 

 (3) , iii Immunogenesis and neoplasia (2) , iv Hemopoietic stem cell systems 

 (5); II. Control of differentiation and neoplasia: i Molecular mechanisms 

 of gene expression (8) , ii Gene expression in early development and cancer 

 (4) , iii Stability of differentiation (5) 



The rationale for this symposium is neatly expressed by Markert in his 

 keynote address: 



In summary, the difficulty with defining and understanding neoplastic 

 change is the same difficulty that developmental geneticists have in under- 

 standing normal cell differentiation. When we understand one, we shall 

 surely understand the other. No one can predict whether progress will be 

 more rapid with a focus on normal cells or on abnormal cells. I believe it 

 is all the same problem - perhaps the most important practical and theoret- 

 ical problem facing us today in the immense area of cell biology. 



219 



