108. 



M.D.COOPER and D.H.DAYTON, eds. 1977. DEVELOPMENT OF HOST DEFENSES 

 Raven, New York. A Monograph of the Nat. Inst, of Child Health and Hijman 

 Development. XIV, 306 pp., 50 figs., 47 tabs., subject index. $ 30.00 



Contributors: Beer, Blaese, Cantor, Colten, Doherty, Gershon, Gill, Klin- 

 man, Lawton, Le Douarin, Melchers, Miller, Mosier, Oldstone, Paul, Raff, 

 Scher, Silverstein, Stagno, Stossel, Tomasi, Vitetta, Wilson 



This volume is based on a conference held in May 1976 as part of a series 

 that views immunology from a broadly developmental perspective. Because this 

 is rapidly becoming a very specialised field the book will appeal most to 

 specialists. Of the 57 contributing authors all but four were Americans. 

 The discussions following the papers are also recorded. 



Most of the 23 papers contain new information, often unpublished at the 

 time of writing. They cover the fetal, perinatal and neonatal development 

 of man and other mammals. Some highlights are new data on the ontogeny of T 

 and B cells and their interactions, on the complement and properdin systems, 

 on phagocytosis and the role of macrophages, and on the function of alpha 

 fetoprotein in immunoregulation. 



109. 



SATELLITE SYMPOSIUM. 1977. Vth INTERNATIONAL CONGRESS OF ENDOCRINOLOGY, 1976 

 Pergamon, Oxford, etc. J. Steroid Biochem. vol.8. 285 pp., numerous figs, 

 and tabs. 



International symposium on hormones in development and growth (mainly mam- 

 malian and human, pre- and postnatal) ; maternal-fetal-placental relation- 

 ships (10 papers); fetal tissues (13); fetal neuroendocrinology (6); sex 

 differentiation (7); discussions recorded. 



110. 



J.B.SOLOMON and J.D.HORTON, eds. 1977. DEVELOPMENTAL IMIvlUNOBIOLOGY 

 Elsevier/North-Holland Biomedical Press, Amsterdam, etc. XXVIII, 456 pp., 

 79 figs., 5 pis., 114 tabs., no indexes. $ 59.95, Dfl. 138.00 



During the last 15 years developmental immunology has become a science in 

 its own right. The present international symposium bears witness to this. 

 It was held in Aberdeen in September 1977 with an attendance of over a 

 hundred scientists from all over the world. A special feature of the sympo- 

 sium was the large number of papers dealing with invertebrates (in the 

 "phylogenetic" section) and lower vertebrates (particularly fish, Xenopus 

 and some reptiles) . All of the 56 contributions are brief research reports 

 or reviews of recent findings. They are reproduced from typescripts without 

 editing. A very useful feature, commendable for other symposia, is the very 

 readable 13-page summary of contents prepared by the editors. 



Two of the three sections are of particular interest to our readers: that 

 on Lymphocyte differentiation (highlighting the emergence and differentia- 

 tion of lymphocyte sub-populations, and cell surface immunoglobulins and 

 antigens)^ and that on Development of antigen-driven immune function (high- 

 lighting T and B cell interrelations in fishes and amphibians, thymectomy 

 in amphibians, immunoglobulin phylogeny, ontogeny of T suppressors and 

 lyraphokines, bursa and immunological responses in the chick, and sequential 

 maturation of the immune response) . 



The book was produced very well and extremely rapidly but has no indexes. 



227 



