Amount of Alcohol Employed. 19 



Although the data given in the preceding paragraph regarding the 

 quantities of alcoholic beverages taken are admittedly not exact, 1 it 

 still seems fair to assume on the basis of the usual alcoholic content of 

 these beverages that two or three times per week during the months 

 covered by experimentation, Subject VI had from 15 to 40 c.c. of abso- 

 lute alcohol. The common amount taken in an evening may have been 

 a near approximation to dose A of these experiments, that is, 30 c.c. of 

 absolute alcohol diluted to a total volume of 150 c.c. The possibility of 

 an additive or prolonged effect serving to reduce the contrast between 

 normal and alcohol experimental days by alcoholic doses following 

 within 48 hours of each other may be assumed as approximately equal 

 in both series. In the Dodge and Benedict series the doses were close 

 together because of the amounts taken outside the Laboratory, and also 

 in the repetition series because the experimental days were consecutive. 2 



During the week of the repetition series of experiments (June 29 to 

 July 4, 1914) the nude weight of the subject varied slightly. The val- 

 ues for the experimental days were in order as follows: 66.9, 67.8, 67.0, 

 66.6, 66.6, 66.4 kilograms. The cup of strong coffee in the morning, 

 mentioned in the personal history, was, as previously stated, omitted 

 from the last meal preceding the experiment. The subject took milk 

 with this meal. 



The outdoor noon temperatures for the six days beginning with June 

 29 were 15.0, 22.8, 15.6, 14.4, 13.9, and 21.7° C. The barometer read- 

 ings at the Nutrition Laboratory were 757.4, 760.0, 766.6, 758.2, 766.1, 

 and 765.3 mm. The Laboratory was not heated and forced draft venti- 

 lation was employed. 



AMOUNT OF ALCOHOL EMPLOYED. 



The alcohol for each day was given in a single portion. The dose 

 used was that designated by Dodge and Benedict as "dose A," which 

 contained 30 c.c. of absolute alcohol, 7 c.c. of orange infusion, 3 1 c.c. of 

 strong infusion of quassia, a slight amount of saccharine for sweetening, 

 and water to bring the volume to 150 c.c. A mixture of the same com- 

 position and volume, but without the alcohol, served as the control dose 

 for each of the three normal days. This regular use of the control 

 mixture constitutes a difference between the two series of measure- 

 ments. Dodge and Benedict (page 24 of their report) finally aban- 

 doned the use of the control mixture, as it proved a failure in com- 

 pletely masking the alcohol. From the standpoint of uniformity it is, 

 however, desirable to give a control dose of some kind, particularly if 

 the actual alcohol dose is not pleasant to take. 



1 The quantities are probably not smaller than reported. 



2 The extra-laboratory use of alcoholic beverages by other Dodge and Benedict subjects is of 

 significance in the interpretation of their individual alcohol results. These data from the original 

 protocols, with certain observations, are embodied in Appendix I of this monograph. (See p. 135.) 



3 Rivers, The influence of alcohol and other drugs on fatigue, London, 190S. 



