69. 



P. L. MORSELLI, S. GARATTINI, and F. SERENI, eds. 1975. BASIC AND THERA- 

 PEUTIC ASPECTS OF PERINATAL PHARMACOLOGY 



Raven, New York. Monographs of the Mario Negri Inst, for Pharmacological Research, 

 Milan. XVI, 440 pp., 181 figs., 84 tabs., subject index. $ 18.95 



This volume embodies the papers read at a symposium held in Milan in June 1974. The 

 contributors are mostly pediatricians and pharmacologists from North America and 

 various Western-European countries. The book will be of most interest to clinicians, but 

 several papers are of potential interest to mammalian embryologists and teratologists. The 

 papers are brief research reports or reviews of recent work. 



Of the 41 papers, most of those that are of interest to our readers are to be found in 

 the sections Placental transfer of drugs and effects on the fetus and the newborn (9 

 papers), Effects of narcotics on the fetus and the newborn (3), and Developmental 

 aspects (7). 



The book is well produced. 



70. 



M. I. SHERMAN and D. SOLTER, eds. 1975. TERATOMAS AND DIFFERENTIATION 

 Academic Press, New York, etc. XVIII, 324 pp., 103 figs., 30 tabs., subject index. 

 $ 16.50, £8.60 



Murine teratomas are of germ cell origin and are composed of tissues derived from all 

 three germ layers. During their early development they consist of cells that closely 

 resemble those of the inner cell mass or embryonic ectoderm of the blastocyst. Advances 

 during the last years have brought out their great potential as model systems for the study 

 of differentiation. 



This report of a symposium held in the U.S.A. in May 1975 is the first book to be 

 devoted entirely to teratomas. A small international community of workers in this area 

 has developed, and it seems that almost every one of them was present or at least 

 represented at the symposium. Most of the 20 papers are research reports or reviews of 

 recent original work. They successively deal with embryo-teratoma relationships, surface 

 antigens, teratoma-host interactions, properties and differentiation control of embryonal 

 carcinoma cells (multipotential stem cells derived from malignant teratomas), and proper- 

 ties of teratomas in vitro (including clonal culture). No discussions are recorded. 



The book is printed in photo-offset and adequately illustrated. It is concluded by a 

 comprehensive bibliography on experimental and spontaneous rodent teratomas. 



REGENERATION, RENEWAL (see also 95,97) 



Textbooks 



71. 



S. M. ROSE. 1974. REGENERATION 



Addison-Wesley, Reading, Mass. Addison-Wesley Module in Biology No. 12. 32 pp., 



16 figs. 



This is a reasonably comprehensive, readable, and well-illustrated account of the main 

 problems in invertebrate and vertebrate regeneration. Understandably, the author places 

 rather much stress on his own work and that of his associates. Key findings from the 

 older Uterature are included. 



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