sufficient to allow of substantive conclusions were omitted. 



The table of contents above speaks for itself. Ch. 5 has a 6-page section on teratogenic 

 effects of drugs. The chapter bibliographies run up to 1972/73, with occasional updatings. 

 They reflect the rather strong bias towards literature pubUshed in EngUsh which is com- 

 mon in books by Anglo-Saxon authors. 



The book is well produced and adequately illustrated. 



102. 



P. W. NATHANIELSZ. 1976. FETAL ENDOCRINOLOGY, an experimental approach 

 North-Holland, Amsterdam, etc. Monographs in Fetal Physiology, vol. 1. XIV, 261 pp., 

 72 figs., 13 tabs., subject index. Dfl. 75.00, $ 30.75 



This monograph is a thorough and critical review of fetal endocrinology against the 

 background of sequential data obtained from the chronically catheterised sheep fetus. The 

 author carefully evaluates the similarities and differences between the sheep and other 

 experimental mammals and man, and devotes much attention to the criteria of physiolo- 

 gical normality during experiments. 



After a general introduction and a chapter on methodology the subject matter is 

 treated partly by organ systems (testis, hypothalamo-hypophysial-portal system, thyroid - 

 two chapters of which one on ruminants -and neurohypophysis), and partly by hormones. 

 A final chapter deals with parturition and the feto-placental unit. An appendix lists 

 methods for the calculation of the production rate of fetal hormones. The endocrinology 

 of carbohydrate and intermediary metaboUsm will be dealt with in a subsequent volume 

 of the series. 



The book is luxuriously produced; it is illustrated mainly with graphs and line dra- 

 wings. The bibliography numbers over 600 titles; I do not know whether this reflects the 

 actual state of things, but it is striking that it contains almost no non-English titles. 



Dissertations 



103. 



X. CHARDONNENS. 1976. LA TOLERANCE AUX ANTIGENES D'HISTOCOMPATI- 



BILITE PENDANT LA METAMORPHOSE DE L'AMPHIBIEN ANOURE, XENOPUS 



LAEVIS: un modele pour I'etude de la tolerance au self 



Ph. D. thesis, Geneve. 173 pp., 10 figs., 9 tabs, (mimeographed) 



Study on larval, metamorphic and adult stages, using skin grafts, mixed lymphocyte 

 reaction and agglutination reaction; conclusions regarding major and minor histocompati- 

 bility systems; evidence for tolerance during metamorphosis. 



Symposium reports 



104. 



M. DURCHON, organizer. 1976. ACTUALITES SUR LES HORMONES DTNVERTE- 



BRES 



Centre Natl, de la Recherche Scient., Paris. Colloques Internat. du C. N. R. S. 25 1 . 5 1 6 pp., 

 156 figs., 40 tabs. Ffr. 130.00 



This international symposium took place in VUleneuve d'Ascq m September 1975. The 

 majority of the participants were from various European countries (with France predomi- 

 nating), but a dozen came from North America. The stress lay on the biosynthesis, meta- 

 bolism and cellular action of invertebrate hormones. Of the 50 contributions at least ten 

 may be of interest to developmental biologists. These deal with hydroids, planarians, 

 annelids (3), molluscs, and insects (5). Three deal specifically with oogenesis in Perinereis 

 and Octopus. 



The papers are in French or English but all have summaries in both languages. The 

 volume is illustrated with line drawings. 233 



