embryologists. Several contain very useful surveys of relevant data in tabular form. 



The book is attractively produced and illustrated mainly with photo- and electron 

 micrographs. 



TERATOGENESIS, CONGENITAL MALFORMATIONS (see also 43,73,79,81,82) 



Treatises 



54. 



H. NISHIMURA and N. OKAMOTO, eds. 1976. SEQUENTIAL ATLAS OF HUMAN 

 CONGENITAL MALFORMATIONS, obser\'ations of embryos, fetuses and newborns 

 Igaku Shoin, Tokyo. VIII, 334 pp., 531 figs., subject index. $ 65.00, Y 16,000,Dfl. 160.00 



This book, written by four Japanese authors, is mainly meant for clinicians as a guide 

 to the supporting embryological evidence for congenital malformations. Some of the 

 material, as well as the bibliography, may be of use to human embryologists. The book 

 is based mainly on an autopsy population of some 6000 embryos (induced abortions) 

 collected in Kyoto and some 6000 fetuses (mainly induced and spontaneous abortions) 

 collected in Hiroshima. 



The bulk of the book consists of some 785 photographs and photomicrographs of 

 mostly good quality, provided with descriptive captions. Most of these are of fuU-term 

 fetuses or neonates, but there are a fair number of earUer stages among them. They are 

 supplemented by brief texts considering, among other things, the pathogenesis and etio- 

 logy (if known) of the malformations. The texts often have explanatory line drawings. In 

 some of these the lettering, pointers and captions are somewhat inadequate. The mal- 

 formations are arranged mainly according to organ systems. 



The bibliography covers 29 pages of small print and consists of literature cited in the 

 text plus selected titles form the world literature. There are five pages of selected litera- 

 ture on normal human development, arranged by organ system. The book is well produced 

 on glossy paper. 



Monographs 



55. 



C. L. BERRY, ed. 1976. HUMAN MALFORMATIONS 



British Council Med. Dept., London. British Med. Bull. vol. 32, 1. 98 pp., 1 1 figs., 2 pis., 



29 tabs. £ 3.50 



Although this issue is obviously meant primarily for members of the medical profession, 

 part of it would be useful collateral reading for those entering the field of teratogenesis. It 

 contains 15 brief reviews, with fairly long to long reference lists, on variety of subjects. 

 About half of these could be of interest to those working in experimental teratology out- 

 side the clinic. 



We specifically mention the papers by Berry and Barlow on reproductive toxicity tes- 

 ting, by Beck on model systems in teratology, by Poswillo on mechanisms and pathoge- 

 nesis of malformation, and by Wolpert on mechanisms of limb development and malform- 

 ation. 



217 



