Dissertations 



56. 



N. CHRISTENSEN. 1 976. OCULAR MALFORMATIONS INDUCED BY RADIATION OF 

 THE MOUSE EMBRYO, a histopathological study with a particular view to stage specificity 

 FADL, Copenhagen; M. D. thesis, Copenhagen. Acta Pathol, et Microbiol. Scand. Sect. A, 

 suppl. 254. 170 pp., 25 figs., 36 tabs. 



Systematic study of gross and microscopic eye malformations after irradiation with 

 mainly 222 R on gestation days 7 through 14; limited dose-response study; data on resorp- 

 tion and embryonic growth retardation; spontaneous eye malformations; good photomicro- 

 graphs. 



57. 



L. DENCKER. 1976. TISSUE LOCALIZATION OF SOME TERATOGENS AT EARLY 



AND LATE GESTATION RELATED TO FETAL EFFECTS 



D. V. M. thesis, Uppsala. Acta Pharmacol, et Toxicol., vol. 39, suppl. 1.131 pp., 41 figs., 

 10 tabs. 



Distribution and localisation of teratogens in pregnant rodents, studied by whole-body 

 autoradiography in sections of whole uteri; teratogens used: heavy metals, trypan blue, 

 2,4,5-T, salicylic acid; stages from presomite till term; quantitation by impulse counting 

 in some cases; many autoradiographs with corresponding light micrographs. 



58. 



E. B. van JULSINGHA. 1976. TWO NEW PROCEDURES FOR USE IN TERATOLOGY 



STUDIES DESIGNED TO EVALUATE THE SAFETY OF AGENTS 



Ph. D. thesis, Utrecht. 31 1 pp., numerous figs, and tabs, (mimeographed) 



I. New procedure for processing results of teratological studies by computer (with flow 

 diagrams); II. Procedure to predict embryo-lethality in rabbits caused by some types of 

 steroids, by determining serum transaminase activities; photographic atlas of freehand sec- 

 tions of head of 29-day rabbit foetus. 



Symposium reports 



59. 



J. D. EBERT and M. MAROIS, eds. 1976. TESTS OF TERATOGENICITY IN VITRO 



North-Holland, Amsterdam, etc. 497 pp., 225 figs., 7 pis., 30 tabs. $ 61.25, Dfl. 150.00 



This international conference was held in Woods Hole, Mass. in April 1975 in honour 

 of Prof. Etienne Wolff and was sponsored by the Institut de la Vie. The title is a little mis- 

 leading: only about a third of the 27 papers have a direct bearing on the area indicated by 

 the title, and some even seem entirely out of place. On the other hand, many authors 

 make an effort to point out the possible teratogenic implications of their findings on 

 basic aspects of normal development as studied in vertebrate cells, tissues and organs in 

 vitro. A great variety of such systems pass in review, usually by estabUshed authorities 

 from many countries. Many contributions are extremely interesting but there is little 

 unity in the volume as a whole. 



The contributions vary greatly in length and format. Most are brief to medium-length 

 reviews of recent work, often unpublished at the time of writing. There has been minimal 

 editing and the conference discussions are not recorded. 



The book is well produced and profusely illustrated; the numerous photographic illus- 

 trations are well reproduced. The book has no indexes. 



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