Studies of Human Organ System Function 



83 



total heat loss or else to compensation for a reduction in 

 the evaporative heat loss. In response to a vasodilating 

 manoeuvre, the temperature rose in the fingers and in the 

 toes in most subjects, but in a varying degree and manner. 





■0, 



Fig. 5. Schema of overlap of hypothetical "true" disease incidence (irregular 

 dark shaded area), clinical classification (tilted rectangles numbered I — IV), 

 and boundary (free form figure) indicating a particular test response or per- 

 formance level which, in this case, is 30-7° C. Seventy-eight subjects and 8 

 patients are represented by the two heavy bordered rectangles; the distri- 

 bution of "positive" and "negative" tests is indicated for the subjects, 

 divided into two age groups. 



For the toes (Fig. 5), the response of subjects between 40 and 

 58 years of age was uniformly good. The average response of 

 younger subjects was even better, although several younger 

 subjects showed little rise. Some old subjects obtained as 

 high a temperature as did some young subjects, but there was 

 an overall significant decrement in the average response with 



