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DISCUSSION 



Dempsey: I am not in a hurry to cross swords with Prof. Zuckerman 

 on this issue. I rather agree with him. I haven't any vast experience 

 in this field, and it has been many years now since I was concerned with 

 this issue. I was interested at that time in making some calculations 

 as to the total number of oocytes present in the guinea pig ovary. 

 When these were counted in the pre-pubertal animal's ovary and the 

 number so obtained was divided by my best estimates of the number 

 of oocytes that were lost during each reproductive cycle, I came out 

 with a figure that was perfectly in agreement with the hypothesis that 

 all the oocytes are formed before puberty. There are plenty of them to 



