172 H. TUCHMANN-DUPLESSIS AND L. MeRCIEK-PaROT 



of the slight difference in weight at birth — 10 per cent lower 

 than the controls, the postnatal development of these young 

 rats is greatly inhibited or arrested. Although we have been 

 able to show that this inhibition appears to be connected with 

 disturbances of lactation, the great frailty of the offspring of 

 cortisone-treated mothers seems to indicate the existence of a 

 more or less reversible change in their constitution. 



Acknowledgement. 



We wish to express our thanks to M. Memin, for taking the 

 photographs. 



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