THE PITUITARY BODY 



pars intermedia, which is the least vascular part of the pitui- 

 tary, survived transplantation best. 



Kasahara (1935) has studied the changes in the cells of the 

 rabbit's pars glandularis when cultures are made of the latter. 

 He found that the proliferating cells were neither chromo- 

 philic nor chromophobic. He described the cultured cells as 

 "deflected epithelium" in distinction from Champy's term 

 "dedifferentiated epithehum." Gaillard (1937) cultured jux- 

 taposed slices of the pars glandularis and the pars neuralis of 

 rats. He observed at the line of contact structural alterations 

 including cysts, which led him to suggest that a similar rela- 

 tionship in vivo accounts for the morphological peculiarities 

 of the pars intermedia. The same author described in another 

 report (1937) cultures of the pars glandularis and other 

 tissues removed from rabbits. Under proper conditions he 

 could recognize oxyphils. He believed that suitably cultured 

 anterior pituitary increases the rate of growth of osteoblasts. 

 Anderson and Haymaker (1935) found that only the chromat- 

 osome-dispersing hormone from the pars intermedia is formed 

 in cultures of the pituitary of rats eight days old. There was no 

 evidence of new secretion of the diuresis-inhibiting hormone 

 (pars neuralis) or of gonadotropic, thyrotropic, or adrenal 

 cortical stimulating hormones (pars glandularis). Their re- 

 sults agree with those of Engel and Werber (1937) but not 

 with those of Nagayama (1937), who was interested only in 

 the formation of gonadotropic hormones. The observations of 

 Gelling and Lewis (1935) are discussed in chapter viii. 



SUMMARY 



The blood supply of the pituitary body is complex. The 

 hypophysio-portal veins, concerning which so much has been 

 written, now appear to be afferent rather than efferent as 

 thought formerly. They correspond, as far as the pars glan- 

 dularis is concerned, to the hepatic portal veins. Also, like 

 the liver, the anterior lobe is furnished with arterial vessels. 

 The bloodsupply of the pars glandularis is quite independent 



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