THE GONADOTROPIC HORMONES 



Much has been written and continues to be written con- 

 cerning "antihormones." There can be no question that gon- 

 adotropic extracts, if repeatedly administered in their 

 present state of impurity, may cause at an unknown site 

 the production of substances circulating in the blood and 

 antagonizing the effects of pituitary extracts. Howev^er, 

 other experiments furnish arguments, so far not refuted, 

 that such substances are not formed in response to gonado- 

 tropic hormone secreted by the intact gland. 



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