MILAN 



Brown et al. (1953) measured BMR's in nine males and seven 

 females at Southampton Island and reported them to be between 124% 

 and 130% of normal. They described their subjects as clinically 

 hypermetabolic but not hyperthyroid in the sense of thyrotoxic. The 

 suggestions of others that the elevated BMR might be due to anemia, 

 polycythemia, racial characteristics, unidentified disease, or the 

 high protein diet were discussed. They have concluded that the high 

 metabolic rate was not entirely the result of a high protein diet, but 

 that the diet is merely another manifestation of the effects of the 

 environment and the food available. 



Thyroid metabolism. Gottschalk et al.(1952) measured the pro- 

 tein bound iodine in seven U. S. soldiers attending an arctic indoc- 

 trination course at Fort Churchill, seven male Eskimos from South- 

 ampton Island, and seven Eskimos from Chesterfield Inlet in winter. 

 There was no change in the soldiers' basal metabolic rate or PBI 

 due to their arctic sojourn. The Eskimos had significantly higher 

 values in PBI (4.2 to9.0 microgram percent) than enthyroid patients 

 in U. S. hospitals. 



131 

 Rodahl et al. (1956, 1957) administered tracer doses of I to 



84 Alaskan coastal and inland Eskimos, 17 Athapascan Indians of Ft. 



Yukon and Arctic Village, and 19 white controls to assess the role of 



thyroid in man during cold exposure. Except for the inland natives, 



there was no s^nificant difference in thyroid uptake or urinary 



elimination of I or in PBI and no seasonal difference in PBI. 



There was no significant difference between natives and whites in 



PBI. The Anaktuvuk Eskimos and the Arctic Village Indians had high 



and rapid uptakes of I which were related to the low iodine in 



their diets and to the hig,h incidence of endemic goiter. A reduction 



rsi 



in the rateof uptakeof I occurred following supplementation daily 

 for 3 months of 0.6 mg postassium iodide. 



Bloo d volumes . Brown et al. (1953) measured blood volumes by 

 dilution of Evans Blue dye and hematocrits in 22 male Eskimos at 

 Southampton Island. They reported blood volumes to be 124% to 142% 



338 



