IMMUNE RESPONSE IN COLD EXPOSURE 



Number of Days 



following Mean Antibody Titer Mean Antibody Titer* 



Initial Injection Cold exposed Non Cold exposed 



1 - 



2 . 



3 . 



if . 



5 1-50 1-20 



6 ** 1-60 1-20 



7 1-60 1-20 



8 1-100 1-60 



9 1-60 1-60 



10 1-100 1-60 



11 1-100 1-60 



12 1-250 1-60 



13 ** 1-500 1-300 

 l** 1-300 1-500 



15 1-1500 1-1000 



16 1-1500 1-1000 



17 1-1500 1-1500 



18 1-3000 1-3000 



19 1-6000 l-UOOO 



20 1-6000 1-4500 



21 1-7000 1-5000 



22 1-7000 1-6000 



23 1-8000 1-7000 



24 1-8000 1-7500 



25 1-10,000 1-8000 



Table VII. Mean precipitin titers of "normal" and "cold exposed" rabbits immunized 



with bovine serum albumin (BSA). ♦Mean titer calculated on the basis of antibody titers 

 obtained from precipitin titrations of nine samples of rabbit antiserum. **Dates of 

 immunization. 



119 



