30 



1 "O 



«» 7 

 ^ 5 



3 



ANTIBODY FORMATION 



T 1 — I r 



T 1 r^ 



u;j O o np n c>- 



• CONTROLS 



O AORENALECTOMIZED 



J- L 



K) 12 



14 



16 18 20 22 24 26 



TIME (WEEKS) 



Figure 5. Circulating antibody levels in bilaterally acirenalectomized and control 

 rabbits immunized with BSA and Freund's adjuvent (10 mg BSA per kg body \\t) at 

 time zero. 



1000 

 700 



I I I I I I 1 I I I I I I I I I 1 I I I I I I 

 • CONTROL 

 2|Vv o HIGH-ALTITUDE 3 



^^ 



I I ' 



30 d. 



2 4 6 8 10 12 14 16 18 20 22 24 26 28 30 

 TIME (WEEKS) 



-^1 



14.150 ft. 



5,280 ft. 



Figure 6. Circulating antibixly levels in rabbits adapted to high altitude and im- 

 munized with BSA (10 mg per kg Ixjdy \i.t) intravenously. 1 indicates the primary in- 

 jection, and 2 and 3 indicate the second and third challenge, respectively. 



97 



