TUNEVALL AND LINDNER 



Survival time, minutes 



o o o 



3 4 5 7 10 12 15 20 30 



Toxin-antitoxin interval, minutes 



Figure 7. Average survival times of groups of normothermic mice given one 

 MLD^OO °^ staphylococcal toxin and, after different intervals, one or four (broken 

 line) neutralizing doses of homologous antitoxin. Same average for a group of five hypo- 

 thermic mice is marked as a single point. 



DISCUSSION 



It should first be pointed out that our experiments involve a 

 procedure for attaining hj^jothermia by the elimination of the 

 normal thermoregulation; thus, hypothermia is reached without 

 stress reactions. 



144 



