Figures 177-187. — Eosinophils from circulating blood — mature, immature, and smudged cells. 



2,470 X. 



Figures 177-183: Normal mature eosinophils that show 

 size range. 



Figures 177-180: Typical eosinophils. The light blue- 

 staining cytoplasmic background is an identifying charac- 

 teristic of these cells; so is the full staining of the nucleus. 



177 The eosinophilic granules can be composed of 4 

 smaller granules in a square. 



178 The eosinophilic granules can appear as scattered 

 small granules on a reticulum. 



179 The eosinophilic granules can have a size range of 

 large to small and be intermingled. 



180 The eosinophilic granules can appear as large spheres 

 with a clear space in the center, with little or no 

 indication that they are made up of 4 smaller 

 granules. 



Figures 181-183: Small normal mature eosinophils, not so 

 common as the larger size. 



181 Eosinophilic granules, closely aggregated. Cell 

 might be confused with a heterophil. 



182 Eosinophilic granules, small and closely aggregated. 



183 Small eosinophil with a high nucleocytoplasmic 

 ratio. 



Figures 184-186: Developmental stages of eosinophils found 

 in circulating blood, 



184 Eosinophilic mesomyelocyte. Strong basophilic cy- 

 toplasm with specific granules in early stages of 

 development. 



185 Eosinophilic metamyelocyte. Later stage of de- 

 velopment than the preceding cell. 



186 Late eosinophilic metamyelocyte, almost fully 

 differentiated. 



Figure 187: Technic artifact. 



187 Smudged eosinophil. The grouping of small gran- 

 ules to form large granules duplicates what was 

 observed in the intact cell, figure 177. 



76 



