208 



PHYSIOLOGICAL REGULATIONS 



autopsy (table 23, column 2) from individuals subjected to water 

 loads and from those not loaded. If F is the fresh weight (wet 

 weight) of the part, then 100(Fi -Fo)/Fo = AV is the change of 

 volume. But the weights of any one organ relative to the control 

 body weights among different autopsied individuals vary (Engels, 

 '04; Stewart, '21 ; Sato, '30) to a degree that makes many compari- 

 sons of organ sizes under diverse water loads of little statistical 

 significance, (b) In one and the same individual, some organ sizes 

 may be mechanically compared before and after water is adminis- 



TABLE 23 



Volume (A.V) and dilution (A-E) in various tissues of growing dogs when water-loaded by 

 consuming diets deficient in water. Values in parentheses are clearly insig- 

 nificant (P > 0.05) ; some others may he also 



trated to the whole body, such as spleen (Barcroft et al., '25) and 

 liver (Reid, '29). Ordinarily anesthesia and other conditions are 

 introduced that need to be specified. This procedure has not yet 

 contributed data in those types of water load in which other cor- 

 relatives were studied in the present investigation, (c) Volumes 

 of distribution may be ascertained repeatedly in one individual. 

 Of particular interest is the congruence of increment in volume of 

 distribution (AVd) with the load of water in the whole body (AW). 

 Among individuals without water load, two measured volumes 

 (fig. 113) appear to be correlated not only with body size, but rela- 

 tive to body size with one another. As measured, the ''plasma" 



