216 



PHYSIOLOGICAL EEGULATIONS 



Both the correlation coefficients and the control samples taken 

 (fig. 119) agree upon the fact that some of the measures of dilution 

 vary in partial independence of water load. These are the mea- 

 sures upon whole blood (A/T, A/Hb), and plasma chloride 

 (A/Clp). Other measures in plasma (A/Dp, A/RIp) vary no more 

 than (C.V.) ± 3 per cent when body load does not change (fig. 119), 

 and show correlation coefficients greater than + 0.5 with modified 

 body loads (table 24). At 1.0-hour intervals the coefficient of dif- 

 ference (CA) is ± 1.3 for A/RIp and ± 2.5 for A/Dp. These two are 

 evidently the types of dilution upon which to rely for accurate 

 reflections of body water load. 



Dog in water excess. 



TABLE 24 



f individuals, 11 tests, 51 observations, 

 and Kingsley {'40) 



New data of Adolph 



As in water excess, so also in water deficit the relation of total 

 water load to various blood dilutions is ascertained (figs. 120 and 

 121). During 3 days of partial water privation the plasma dilu- 

 tion decreases steadily and in parallel to water load (weight) of the 

 whole body. Upon sudden ending of the privation, water is drunk 

 ad libitum (fig. 120), whereupon the amount ingested exceeds the 

 amount lost. When drinking is limited to the amount of weight 

 deficit (fig. 121) the changes of plasma dilution are again in marked 

 contrast to those of fig. 116. {a) At 0.2 hour a slight concentration 

 of plasma regularly occurs, (h) Dilution proceeds much more 

 slowly than without previous deficit, (c) Even at 1.0 hour dilution 

 is scarcely maximal, (d) The plasma dilution is greater after pri- 

 vation than without it, though the same amounts of water are 

 ingested. 



Correlations, within these tests of privation and recovery, be- 



