94 



Britton Chance 



290pM 

 ADP 



t 



ZI 



60 

 sec 





\ 



-240jjM O2 



Fig. 2A. Illustration of the lack of respiratory control in 

 heart sarcosomes suspended in saline medium. The addition 

 of a small concentration of ADP accelerates respiration, but 

 thereafter no appreciable deceleration occurs. (Expt. no. 305) 



^im 



465'|jM 

 ADP 



Fig. 2B. Control of respiration of a heart 

 sarcosome preparation ; sucrose - ethylene- 

 diaminetetra-acetic acid medium, a Kg as 

 substrate. Note that the respiration rate 

 decelerates abruptly when the added ADP 

 has been expended. (Expt. no. 615) 



