Subject Index 



383 



Glycolysis, 



enzymes limiting, 207-209 



feedback in, 215 



in ascites tumours, 205-229 



increase of, 81 



in malignant and non-malignant 



cells, 227 

 limiting factors in, 205-229 

 regulation of, experimental method 

 231-232 

 role of triphosphopryidine 

 nucleotide, 230-255 

 regulation of by reduced triphos- 

 phopyridine nucleotide, 243-247 

 regulation of by triphosphopyrid- 

 ine nucleotide, effect of im- 

 purities, 240-242 

 regulation of by triphosphopyrid- 

 ine nucleotide, effect of mito- 

 chondria, 238-240 

 role of inorganic phosphate, 259 

 triphosphopyridine nucleotide-lac- 

 tic dehydrogenase in, 244-245 

 Glycolytic enzymes, in ascites 



tumour cells, 206-207 

 Glycolytic pathway, of carbo- 

 hydrate metabolism, 152-154, 

 186, 187 

 in carbohydrate metabolism re- 

 lative importance of, 167-170 

 Glycolytic systems, 14, 15, 35 

 Gramicidin, as uncoupling agent, 



133-134, 138 

 Growth, in bacteria, 311-320 

 Guanine, in cell growth, 339, 341, 



350 

 Guanosine 5- 'phosphate, 306, 307 

 Guanylic acid, synthesis of, 306-307 



Heart muscle, respiration in, 3-8, 



11 

 Heart sarcosomes, respiratory con- 

 trol in, 61, 64 

 Hexokinase, activity of, 47 



effect on oxidative phosphoryla- 

 tion, 30-34 



in carbohydrate metabolism, 34— 

 36, 39, 40-41 



in cell respiration, 15-16 



in glycolysis, 207, 208 

 Hexose monophosphate, synthesis 



of, 72-73 

 Hexose monophosphate pathway 



in carbohydrate metabolism, 



155-157, 161 



Histidine, in Aerobacter aerogenes, 



364-365 

 Hormonal effects of oxidative 



pathways, 171-173 

 Hydrofolic acid, in carbohydrate 



metabolism, 160 

 Hydrolases, location of in cells, 



51-52 

 p-Hydroxybutyrate, effect on oxi- 

 dative phosphorylation, 196-197 



oxidation of, 133, 140 

 DL-p-Hydroxybutyrate, in oxidative 



phosphorylation, 77, 88 



Inosine 5'- phosphate, 306, 307, 308 

 Intracellular structure, effect on 



metabolic regulation, 17-49 

 Iron porphyrins, in cell respiration, 



4 

 Isoleucine, 309 



a-Ketoglutarate, formation of, 283 

 in carbohydrate metabolism, 153, 



160 

 in control of cell respiration, 112- 



113 

 in oxidative phosphorylation, 72, 

 73, 76, 77 

 Krebs cycle pathway of carbo- 

 hydrate metabolism, 152-154 



L-Lactate, effect on cell respiration, 

 3, 6, 7 



Lactic acid production, effect of 

 anaerobic conditions, 210 

 effect of 2 : 4-dinitrophenol, 210 

 effect of inorganic phosphate, 210- 



212 

 enzymes in, 207-208 



Lactic dehydrogenase, in carbo- 

 hydrate metabolism, 160 



Lactose -positive bacteria, 326 



Lipids, uncoupling by, 70-71 



Liver, oxidative pathways in, 171- 

 173 



Liver tumours, carbohydrate meta- 

 bolism in, 173-174, 176 



Lysosomes, 51-52, 53, 56 



Magnesium, effect on adenosine 

 triphosphate, 146, 148 

 effect on phosphorylation efficiency 

 of mitochondria, 101, 103, 127 

 Malic dehydrogenase, 161, 164 



