WOUND HEALING IN EMBRYOS 259 



The wound- healing of later emhryonic stages is even more remarkable than that of 

 single cells- More than half of the epidermis of a neurula may he pealed off and within 

 a day or so the remaining epidermis will spread to form a very thin covering epithelium 

 over the exposed or uncoated enio-mesoderm. Cell multiplication plays no significant role 

 in this healing process. Former cylindrical cells of a spreading epithelium may hecome 

 flattened out into a squamous epithelium. 



BEFERENCE S : 



Arey, L. B. , 1952 - "Certain haslc principles in wound healing." Anat. Eec. 51* 



Baitsell, G. A., I916 - "The origin and structure of a fihrous tissue formed in wound 

 healing." Jour. Exp. Med. 25:759- 



Barber, L, W., 19^^ - "Correlations between wound healing and regeneration in fore-limbs 

 and tails of lizards." Ant. Bee. 89:'^'+l. 



Bentley, F. H., 195 6 - "Wound healing in vitro." Jour. Anat. 70:i+98. 



Burr, H. S., S. C. Harvey, M. Taffel, I958 - "Bio-electric correlates of wound healing." 

 Yale Jour. Biol. & Med. 11:103- 



Burr, H. S., M. T, Taffel, S. C. Harvey, I9U0 - "An electrometric study of the healing of 

 wound in man." Yale Jour- Biol. & Med. 12:1^5- 



Chambers, E., V^kO - "The relation of extraneous coats to the organization and permeabil- 

 ity of cellular membranes." Symp. on Quant. Biol. 8:1'*'+. 



Eycleshymer, A. C, I907 - "The closing of wounds in the larvae Necturus." Am. Jour. Anat. 



7. 



Galtsoff, P- S-, 1925 - "Begeneration after dissociation." Jour. Exp. Zool. U2:l83. 



Harrison, B. G., 191*+ - "The reaction of embryonic cells to solid structures." Jour. Exp. 

 Zool. 17:521. 



Harrison, Boss G., 19'+7 - "Wound healing and reconstitutlon of the central nervous sys- 

 tem of the amphibian embryo after removal of parts of the neural plate." Jour- 

 Exp. Zool. 106:27. 



Harvey, E. N- & G. Fankhauser, 1955 - "The tension at the surface of eggs of the salaman- 

 der, Trlturus viridescens . " Jour. Cell. & Comp. Physiol. ^-.kG^. 



Helff, 0. M., 1951+ - "Mitogenetic rays and wound healing." Jour. Exp. Zool. 68:5^7. 



Holtfreter, J-, 19'+5 - "Properties and functions of the surface coat in amphibian egga." 

 Jour. Exp. Zool. 95:251. 



Holtfreter, J., I9U5 - "A study of the mechanics of gastrulatlon- " Jour. Exp. Zool. 

 9l+:26l. (see page 292) 



Jenkinson, J. W., I906 - "On the effects of certain solutions upon the development of the 

 frog's egg." Arch. f. Ent. mech. 21:567. 



Ossowskl, H. E., 191*+ - "Uber aktive Zellbewegungen Im Explantat von Wirbeltierembryonen. " 

 Arch. f. Ent. mech. 58:5'+7. 



Taffel, M., & S. C. Harvey, I958 - "Effect of absolute and partial vitamin C deficiency 

 on wound healing." Proc. Exp. Biol. & Med. 58:518. 



Zimmerman, L. & B- Bxjgh, 191+1 - "Effect of age of the development of the egg of the 

 leopard frog, Bana pipiens." Jour. Morph. 68:529. 



Zorzoli, A., I9I+6 - "Effects of vital dyes on early development of the amphibian embryo." 

 Proc. Soc. Exp. Biol. & Med. 65:565. 



(Note: See also references under section on "Osmo-regulation" . 



