STUART, D. G. 
Results. In two animals electrodes were inserted into the sep- 
tum but no current was passed. These animals recovered within a 
week but were not subjected to cold stresses. Table X lists the 
ratios of shivering/resting VO as determined 26 to 50 days after 
surgery in the remaining 8 cats. As shown, all these animals could 
shiver as effectively as the intact cats whose shivering/resting 
VO„'s are listed in Table VI. Additionally, the drops in rectal 
2 , o o 
temperature/unit time in C to 5 C environment were within the 
range shown for intact cats in Table VI. On the basis of these ex- 
periments no differences were observed in animals with complete, 
medial or lateral mid and posterior septal lesions. In Cat No. S 13 
both the posterior septal (Fig. 27B) and preoptic (Fig. 27C) regions 
were destroyed. The preoptic tissue was destroyed to sever the in- 
tact anterior septal (Fig. 27A) connection with the diencephalon. 
Figure 28 shows a bilateral medial septal lesion in Cat No. S 11 
and Figure 29 a bilateral lateral septal lesion in Cat No. S . In 
this latter case possibly the entire posterior septal connection 
with the diencephalon was destroyed (Fig. 29C). 
For the first two weeks after surgery these animals were 
hypokinetic and made no attempts to escape when their cage doors 
were left open. They were capable of chewing and swallowing food 
placed in their mouths but would not eat of their own volition. They 
did not assume bizarre postures and if compelled to move had 
normal locomotive control. When tested, all animals had regained 
their preoperative weights by their own spontaneous eating. One cat, 
S , refused to eat, vomited tube-fed food, yet was capable of 
chewing and swallowing food placed in her mouth. This cat died 24 
days after surgery with a weight of 1.4 kg., as compared to her 
preoperative weight of 2.4 kg. From the third day after surgery 
until death, this cat had normal locomotor movements and a normal 
body temperature. Due to faulty fixation and presentation the brain 
was unsuitable for histological inspection, but the extent of tissue 
destruction was stereotaxically aimed to be similar to Cat S . 
Comments. In a recent review of anatomical stimulation and 
ablation studies of telencephalohypothalamic relationships, Gloor 
(1956) concluded that the limbic system of the telencephalon "is not 
critically involved in the integration of the very same somato- 
autonomic mechanisms which it is apt to influence on electrical 
stimulation..." His conclusion is well exemplified in these particular 
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