CENTRAL AND PERIPHERAL MECHANISMS 
his original paper saying that they had only been able to get it in 
animals under urethane or under ether. This was our experience 
also. We did not get it under phenobarbital except in one instance. 
The people in Sweden have also found it only under chloralose and 
urethane anesthesia. Hess reported that he only saw it in cases 
where he was making lesions by local heating, but never in the 
course of minimal diathermy. Dr. Hemingway, what is your ex- 
perience in conscious animals? How high do you have to heat to get 
this response? 
DR. HEMINGWAY: We were not able to produce panting by 
heating the anterior hypothalamus with diathermy, but we were able 
to stop shivering and cause cutaneous vasodilation. During such ex- 
periments we could not measure the hypothalamic temperature 
except very roughly — perhaps to one-half or one degree. This was 
due to the diathermy current interfering with the temperature 
measurements. All of our measurements, therefore, had to be de- 
termined after the diathermy current had been turned off, during 
which time the temperature was falling quite quickly. Typically, 
heating of the anterior hypothalamus cause a cutaneous vasodilation, 
a cessation of shivering, but no panting. 
DR. LIM: Was there any increase in respiratory rate, say, in 
terms of so-called pre-panting hyperpnea? 
DR. HEMINGWAY: No indication at all. 
DR. HENSEL: We saw the onset of panting in the unanesthetized 
cat, during local hypothalamic rewarming. 
DR. HEMINGWAY: Where were you heating it? 
DR. HENSEL: In the anterior hjrpothalamus. 
DR. LIM: Dr. Hammond, in Dr. Hardy's group, produced it in 
the unanesthetized dog. 
DR. HEMINGWAY: Dr. Magoun reported it in the anesthetized 
cat, but he was heating the anterior hypothalamus. I was using dogs, 
unanesthetized dogs. 
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