HISTORICAL REVIEW 
DR. STUART: In our experiments the method of cooling has 
been critical. The animal might display a generalized avoidance 
response to a stimulus that is nocioceptive as well as cold. 
DR. CLARK: That is hard to accept under the conditions of our 
experiment. 
DR. STUART: It is easy to accept under the conditions of mine. 
DR. HEMINGWAY: Is it possible that a small amount of tissue 
is left just above the cerebral peduncle? 
DR. CLARK: What I am saying is that we found that these are 
usually cases where a complete transection was attempted, where 
the knife skipped a little bit over the bottom, so that only part of the 
peduncle is left and everything above it is gone. 
MR. ADAMS: I believe there is supportfor Dr. Clark's remark 
in studies that were conducted a long time ago where it was shown 
that vasomotor changes were associated with environmental temper- 
ature changes. 
DR. HEMINGWAY: But they are almost ineffective in preventing 
a fall in rectal temperature in the cold. 
MR. ADAMS: In this type of preparation one should not argue 
that the vasomotor changes are completely ineffective. 
DR. HEMINGWAY: There may be a tremor in a decerebrate 
preparation. Bard and Stuart have observed a tremor which appears 
in the cold and disappears with warmth, but this tremor is ineffec- 
tive in temperature regulation. 
DR. CLARK: I agree with you; it is not particularly useful 
because the animal's temperature falls markedly, but it is an indi- 
cation, primarily, that the pathway is quite diffuse. 
DR. HEMINGWAY: Yes, I would agree with that. 
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