RODDIE, I. C. 
DR. FREEMAN: Dr. Stuart and I were wondering the other day 
just how much therm o-responsiveness these vasomotor areas have 
in the spinal animal. 
DR. RODDIE: I have really no information about that at all. 
DR. FREEMAN: One of the old-fashioned neurological reflexes 
that can be elicited in a spinal man is erection of pilomotors, that 
is, goose flesh. If nocioceptive stimulus is applied to the foot, let us 
say, and one can evoke goose flesh all over the lateral extremity, 
this would imply that there are some mass reflex type activities 
which may not be specifically related to goose flesh. Those mech- 
anisms are still there, but they are not tied into the rigjit stimulus. 
There is obvious vasomotor activity of some sort, but is it related 
to temperature changes? Have you had any experience on this. Dr. 
Hensel? 
DR. HENSEL: No. Another question. How didyou test the effec- 
tiveness of your atropine infusion? 
DR. RODDIE: By giving an infusion of acetylcholine before and 
afterwards. The effect of acetylcholine will be abolished after 
infusion. In addition, in the heating experiment, we could tell how 
long the atropine was effective by the length of time we were able 
to abolish sweating. 
DR. HENSEL: Did you test with acetylcholine in the heating 
experiments? 
DR. RODDIE: Yes, the vasodilation which occurs in the skin is 
depressed and delayed by atropine. However, it is not abolished. 
Rather, as in the sub- mandibular salivary gland, it is still detect- 
able. However, even at a time whenthe blood flow in the forearm is 
rapidly rising, we still find that the effect of injected acetylcholine 
is still abolished. The situation in the skin, therefore, seems to be 
analogous to that seen in the sub- mandibular salivary gland. 
.42 
