viii CONTENTS 



PAGE 



Oxygen Consumption of Mammalian Tissue at Reduced Temperatures — 



F. A. Fuhrman 50 



Temperature coefficients of isolated tissues at various temperatures. Oxygen de- 

 livery from 0° to Z7° C. 



Respiratory Physiologic Studies During Hypothermia — /. W. Severinghans 



and M. Stupfel 52 



Validity of usual nomograms for pOe and pC02. Temperature corrections. Deter- 

 mination of pK'. Pulmonary ventilation and blood gases ; dead space, distribution, 

 pH, compliance. 



The Gas Transport System in Hypothermia — F. F. Kao 58 



Ventilation, cardiac output, and oxygen consumption. Effect of shivering. 



Hypothermia in the Unanesthetized Poikilothermic Dog — A. D. Keller 61 



Completely and partially poikilothermic dog. Basal heat production. Temperature 

 coefficient for heat production. Cold-stimulated nonshivering heat production. Renal, 

 cardiovascular, and cerebral function in hypothermia. 



Discussion: 



A. C. Burton, J. IV. Severinghaus, and J. Calm 78 



Physiology of Hibernation in Mammals — C. P. Lyman and P. 0. Chat field . . 80 



Deep hibernators. Hibernation vs. hypothermia. Preparation for hibernation : fat 

 and food storage, brown fat, endocrines. Entering hibernation. In hibernation : 

 metabolism, nervous system, acid-base, blood sugar, blood growth, periodic awaken- 

 ing. Arousal: general, circulation (heart, blood pressure), heat sources, metabolism, 

 nervous system. Theories. 



Discussion: 



A. C. Burton, A. D. Keller, E. Calkins, G. E. Burch, J. D. McMurrey, 



H. Swan, C. McC. Brooks, and R. K. And jus 122 



Resuscitation and Recovery of Hypothermic, Supercooled, and Frozen Mam- 

 mals — R. K. Andjus, J. E. Lovelock, and A. U. Smith 125 



A. Summary of Sound Film: Rats cooled to 0°C. Respiratory and cardiac arrest. 

 Successful rewarming with microwaves. Golden hamsters frozen at — 0.6° C. Suc- 

 cessful rewarming with diathermy. Hamsters supercooled to — 5° C. Monkeys 

 cooled to -|- 5° C, and reanimated. B. Addenda. Distribution of ice in hamsters 

 at — 5° C. Closed container technique of cooling : critical fall of oxygen tension, 

 oxygen debt, role of O2 and CO2. Physiology of induced hypothermia : the hypo- 

 thermic states, maintained hypothermia, the range of active defense, cold narcosis 

 and suspended animation, after-effects, repeated cooling. 



Discussion: 



F. J. Lewis, J. W. Severinghans, Jl'. Parkins, .1. L. Hopkins. J. Fine, 



R. W. Brauer, F. D. Moore, R. D. Dripps, and J. Henley 143 



